Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.66 |
| ▸ | ACHE | P22303 | 7/20 | 0.52 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.52 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11780042 | 1.00 | EPHX1 (0.66) | EPHX1ACHEZDHHC20ZDHHC2CASP2 | |
| SCHEMBL7790364 | 0.92 | ACHE (0.59) | EPHX1ACHE | |
| SCHEMBL13583543 | 0.83 | EPHX1 (0.63) | EPHX1ACHEZDHHC20ZDHHC2CASP2 | |
| SCHEMBL3746705 | 0.83 | EPHX1 (0.63) | EPHX1ACHEZDHHC20ZDHHC2CASP2 | |
| SCHEMBL3663444 | 0.83 | EPHX1 (0.63) | EPHX1ACHEZDHHC20ZDHHC2CASP2 | |
| SCHEMBL7966153 | 0.81 | EPHX1 (0.60) | EPHX1ACHEZDHHC20ZDHHC2CASP2 | |
| SCHEMBL1416150 | 0.80 | TDP1 (0.47) | EPHX1ACHE | |
| SCHEMBL3910901 | 0.79 | EPHX1 (1.00) | EPHX1ACHECASP2MGLL | |
| SCHEMBL22693961 | 0.79 | EPHX1 (1.00) | EPHX1ACHECASP2MGLL | |
| SCHEMBL1616893 | 0.79 | EPHX1 (1.00) | EPHX1ACHECASP2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904556-A2 | POLYASPARTIC ACID DERIVATIVES IN COVERING AGENTS CONTAINING POLYSILOXANE | Lanxess Deutschland GmbH (DE) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007003264-A2 | POLYASPARTIC ACID DERIVATIVES IN COVERING AGENTS CONTAINING POLYSILOXANE | LANXESS DEUTSCHLAND GMBH (DE) | 2007-01-11 | — | — | WO | disclosed |
| EP-1518881-A2 | Polymer modified by a polyether as adjuvant in leather manufacture | Bayer Chemicals AG (DE) | 2005-03-30 | — | — | EP | disclosed |
| US-20050058619-A1 | Polyether-modified polymers as leather auxiliaries | LANXESS DEUTSCHLAND GMBH (DE) | 2005-03-17 | — | — | US | disclosed |
| EP-0842300-B1 | USE OF POLYASPARTIC ACID AMIDES AS LEATHER AUXILIARY PRODUCTS | BAYER AG (DE) | 2001-11-07 | — | — | EP | disclosed |
| US-6254644-B1 | LOW-METAL SALT TANNING WITH A REACTIVE ORGANIC TANNING AGENT, ALDEHYDES OR BISULPHITE-BLOCKED POLYISOCYANATES, AND RETANNING WITH POLYASPARTIC ACID AND/OR POLYASPARTAMIDES, FINISH OF POLYURETHANE AND/OR POLYESTERAMIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-03 | — | — | US | disclosed |
| EP-0963445-A1 | BIOLOGICALLY DEGRADABLE LEATHER | BAYER AG (DE) | 1999-12-15 | — | — | EP | disclosed |
| CN-1231286-A | 1,2-Di-substituted piperidine derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO LTD (JP) | 1999-10-13 | — | — | CN | disclosed |
| US-5885474-A | TREATING LEATHER WITH MODIFIED POLYSUCCINIMIDE AND FIXING THE LEATHER BY ADDITION OF CHROMIUM, ALUMINUM, ZIRCONIUM OR TITANIUM COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |
| WO-1998038340-A1 | BIOLOGICALLY DEGRADABLE LEATHER | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-03 | — | — | WO | disclosed |
| EP-0842300-A1 | USE OF POLYASPARTIC ACID AMIDES AS LEATHER AUXILIARY PRODUCTS | BAYER AG (DE) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997006279-A1 | USE OF POLYASPARTIC ACID AMIDES AS LEATHER AUXILIARY PRODUCTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050058619-A1 | Polyether-modified polymers as leather auxiliaries | PUF60, B2M, CBR3 | EPHX1 3012/4885ACHE 3981/4885ZDHHC20 873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.