Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335892 | 0.87 | TAAR1 (0.41) | TAAR1HTR2AHRH1AOC3TRPA1 | |
| SCHEMBL335258 | 0.72 | — | — | |
| SCHEMBL6546282 | 0.67 | CYP2D6 (0.59) | TAAR1CACNA1CHTR2AHRH1TRPA1 | |
| SCHEMBL335854 | 0.67 | LMNA (0.42) | TAAR1HTR2AHRH1AOC3TRPA1 | |
| SCHEMBL3627329 | 0.66 | LMNA (0.50) | TAAR1HTR2AHRH1AOC3TRPA1 | |
| SCHEMBL335496 | 0.66 | TAAR1 (0.56) | TAAR1HTR2AHRH1AOC3TRPA1 | |
| SCHEMBL9555071 | 0.65 | TAAR1 (0.43) | TAAR1HTR2AHRH1AOC3TRPA1 | |
| SCHEMBL14258186 | 0.65 | TAAR1 (0.60) | TAAR1HTR2AHRH1AOC3 | |
| SCHEMBL8127199 | 0.65 | AOC3 (0.43) | TAAR1HTR2AHRH1AOC3TRPA1 | |
| SCHEMBL7537440 | 0.65 | TAAR1 (0.43) | TAAR1HTR2AHRH1AOC3TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139762-A1 | Metallocene Compounds, Ligands Used in Their Preparation, Preparation of 1-Butene Polymers and 1-Butene Polymers Therefrom | BASELL POLYOLEFINE GMBH (DE) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139762-A1 | Metallocene Compounds, Ligands Used in Their Preparation, Preparation of 1-Butene Polymers and 1-Butene Polymers Therefrom | CHRM1, B2M, CHRM2 | TAAR1 586/4885CACNA2D1 3156/4885CACNB2 3056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.