Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547617 | 0.88 | SMN1; SMN2 (0.50) | CYP2D6TRPA1SLC6A2SIGMAR1TAAR1 | |
| SCHEMBL6548084 | 0.88 | CYP2D6 (0.52) | CYP2D6TRPA1SLC6A2SIGMAR1TAAR1 | |
| SCHEMBL12604145 | 0.86 | ESR1 (0.53) | CYP2D6TRPA1SLC6A2SIGMAR1TAAR1 | |
| SCHEMBL12604223 | 0.83 | MEN1 (0.56) | CYP2D6SIGMAR1SLC6A4 | |
| SCHEMBL30934 | 0.83 | TRPA1 (0.77) | CYP2D6TRPA1SLC6A2SIGMAR1TAAR1 | |
| SCHEMBL10599610 | 0.82 | SIGMAR1 (0.52) | CYP2D6TRPA1SLC6A2SIGMAR1TAAR1 | |
| SCHEMBL20906818 | 0.82 | SLC6A2 (0.49) | TRPA1SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL1140503 | 0.80 | TRPA1 (0.74) | CYP2D6TRPA1SLC6A2SIGMAR1TAAR1 | |
| Water SCHEMBL3896311 | 0.80 | TRPA1 (0.74) | CYP2D6TRPA1SLC6A2SIGMAR1TAAR1 | |
| SCHEMBL9747206 | 0.80 | TAAR1 (0.50) | CYP2D6TRPA1SLC6A2SIGMAR1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717098-B1 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON MITSUBISHI OIL CORP (JP) | 2004-01-21 | — | — | EP | disclosed |
| US-5817251-A | AROMATIC HYDROCARBON LUBRICANT | NIPPON OIL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5711895-A | Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group | NIPPON OIL CO., LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0717098-A2 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON OIL CO. LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |