Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.94 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.94 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.94 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.94 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | CDC25B | P30305 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | HTT | P42858 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | S100A4 | P26447 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 2/20 | 0.58 |
| ▸ | TDP2 | O95551 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dichlon SCHEMBL9751236 | 0.97 | IDO1 (1.00) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| Dichlon SCHEMBL45723 | 0.97 | IDO1 (1.00) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| Dichlon SCHEMBL29360991 | 0.97 | IDO1 (1.00) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| Dichlon SCHEMBL28269079 | 0.94 | IDO1 (0.94) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| Dichlon SCHEMBL10794085 | 0.94 | IDO1 (0.94) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL7645623 | 0.92 | IDO1 (0.89) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| Dichlon SCHEMBL10881472 | 0.87 | IDO1 (0.80) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| Dichlon SCHEMBL9560455 | 0.85 | IDO1 (0.76) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL24660102 | 0.83 | DNMT1 (0.75) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL29881216 | 0.83 | IDO1 (0.75) | IDO1DNMT1DNMT3LDNMT3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497374-B1 | FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | GEN ELECTRIC (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1497374-A1 | FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | GENERAL ELECTRIC COMPANY (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087226-A1 | FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | GENERAL ELECTRIC COMPAMY (US) | 2003-10-23 | — | — | WO | disclosed |