Dichlon

Dichlon

SCHEMBL9560455

O=C1C(Cl)=C(Cl)C(=O)c2ccccc21.O=C1C=CC(=O)c2ccccc21

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.76
DNMT1 P26358 1/20 0.76
DNMT3L Q9UJW3 1/20 0.76
DNMT3A Q9Y6K1 1/20 0.76
CDC25B P30305 5/20 0.67
MAOA P21397 3/20 0.67
MAP2K1 Q02750 2/20 0.67
MAOB P27338 2/20 0.67
SNCA P37840 2/20 0.67
AKT1 P31749 1/20 0.67
PIN1 Q13526 1/20 0.67
EHMT2 Q96KQ7 1/20 0.67
NSD1 Q96L73 1/20 0.67
EHMT1 Q9H9B1 1/20 0.67
MEN1 O00255 7/20 0.50
KMT2A Q03164 7/20 0.50
MAPT P10636 8/20 0.48
LMNA P02545 6/20 0.48
HTT P42858 5/20 0.48
MAPK1 P28482 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dichlon SCHEMBL9751236 0.87 IDO1 (1.00) IDO1DNMT1DNMT3LDNMT3ACDC25B
Dichlon SCHEMBL45723 0.87 IDO1 (1.00) IDO1DNMT1DNMT3LDNMT3ACDC25B
Dichlon SCHEMBL29360991 0.87 IDO1 (1.00) IDO1DNMT1DNMT3LDNMT3ACDC25B
Anthraquinone SCHEMBL5162013 0.85 IDO1 (0.82) IDO1DNMT1DNMT3LDNMT3ACDC25B
Dichlon SCHEMBL10794085 0.85 IDO1 (0.94) IDO1DNMT1DNMT3LDNMT3ACDC25B
Dichlon SCHEMBL28269079 0.85 IDO1 (0.94) IDO1DNMT1DNMT3LDNMT3ACDC25B
Dichlon SCHEMBL5077878 0.85 IDO1 (0.94) IDO1DNMT1DNMT3LDNMT3ACDC25B
Dichlon SCHEMBL10881472 0.83 IDO1 (0.80) IDO1DNMT1DNMT3LDNMT3ACDC25B
SCHEMBL7645623 0.82 IDO1 (0.89) IDO1DNMT1DNMT3LDNMT3ACDC25B
9,10-Phenanthrenequinone SCHEMBL9192681 0.82 IDO1 (0.78) IDO1DNMT1DNMT3LDNMT3ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0552223-A1 USE OF BENZENE DERIVATIVES AS CHARGE TRANSFER MEDIATORS. NOVO NORDISK AS (DK) 1993-07-28 EP disclosed
WO-1992007263-A1 USE OF BENZENE DERIVATIVES AS CHARGE TRANSFER MEDIATORS NOVO NORDISK A/S (DK) 1992-04-30 WO disclosed