Dichlon

Dichlon

SCHEMBL9751236

O=C1C(Cl)=C(Cl)C(=O)c2ccccc21.O=C1C(Cl)=C(Cl)C(=O)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 1.00
DNMT1 P26358 1/20 1.00
DNMT3L Q9UJW3 1/20 1.00
DNMT3A Q9Y6K1 1/20 1.00
MEN1 O00255 5/20 0.65
KMT2A Q03164 5/20 0.65
CDC25B P30305 4/20 0.65
MAPT P10636 6/20 0.61
HTT P42858 5/20 0.61
LMNA P02545 4/20 0.61
NPC1 O15118 4/20 0.61
RAB9A P51151 4/20 0.61
MAPK1 P28482 3/20 0.61
NPSR1 Q6W5P4 3/20 0.61
S100A4 P26447 3/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
KDM4E B2RXH2 2/20 0.61
POLB P06746 2/20 0.61
APAF1 O14727 2/20 0.61
TDP2 O95551 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dichlon SCHEMBL29360991 1.00 IDO1 (1.00) IDO1DNMT1DNMT3LDNMT3AMEN1
Dichlon SCHEMBL45723 1.00 IDO1 (1.00) IDO1DNMT1DNMT3LDNMT3AMEN1
Dichlon SCHEMBL28269079 0.97 IDO1 (0.94) IDO1DNMT1DNMT3LDNMT3AMEN1
Dichlon SCHEMBL5077878 0.97 IDO1 (0.94) IDO1DNMT1DNMT3LDNMT3AMEN1
Dichlon SCHEMBL10794085 0.97 IDO1 (0.94) IDO1DNMT1DNMT3LDNMT3AMEN1
SCHEMBL7645623 0.94 IDO1 (0.89) IDO1DNMT1DNMT3LDNMT3AMEN1
Dichlon SCHEMBL10881472 0.89 IDO1 (0.80) IDO1DNMT1DNMT3LDNMT3AMEN1
Dichlon SCHEMBL9560455 0.87 IDO1 (0.76) IDO1DNMT1DNMT3LDNMT3AMEN1
SCHEMBL24660102 0.86 DNMT1 (0.75) IDO1DNMT1DNMT3LDNMT3AMEN1
SCHEMBL29881216 0.86 IDO1 (0.75) IDO1DNMT1DNMT3LDNMT3AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0293400-A4 METHOD FOR CONTROLLING PLANT DISEASES AND MICROORGANISMS IN THE PRESENCE OF PLANTS 1991-09-11 EP disclosed
US-4925866-A APPLYING AQUEOUS N-HALOHYDANTOIN SOLUTION GREAT LAKES CHEMICAL CORPORATION (US) 1990-05-15 US disclosed
EP-0293400-A1 METHOD FOR CONTROLLING PLANT DISEASES AND MICROORGANISMS IN THE PRESENCE OF PLANTS GREAT LAKES CHEMICAL CORPORATION (US) 1988-12-07 EP disclosed
WO-1988002987-A1 METHOD FOR CONTROLLING PLANT DISEASES AND MICROORGANISMS IN THE PRESENCE OF PLANTS GREAT LAKES CHEMICAL CORPORATION (US) 1988-05-05 WO disclosed
US-4113804-A FILMS, PIPES, ADHESIVES SOUTHERN CHEMICAL COMPANY (US) 1978-09-12 US disclosed