Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811127 | 0.84 | CA12 (0.52) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL812138 | 0.80 | ALDH1A1 (0.51) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL3038961 | 0.80 | ALDH1A1 (0.51) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL10364646 | 0.79 | MTNR1A (0.54) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL22472000 | 0.77 | KMT2A (0.49) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL17355067 | 0.76 | KMT2A (0.51) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL20690973 | 0.75 | KMT2A (0.58) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL811674 | 0.75 | KMT2A (0.53) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8131223 | 0.75 | ALDH1A1 (0.54) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL12304473 | 0.75 | CYP1A2 (0.51) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329715-B2 | Abrasion resistant coatings by siloxane oligomers | YAZAKI CORPORATION (JP) | 2008-02-12 | — | — | US | disclosed |
| US-20060235178-A1 | Abrasion resistant coatings by siloxane oligomers | STOWE WOODWARD LLC | 2006-10-19 | — | — | US | disclosed |