Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21552131 | 0.91 | GPR84 (0.50) | TSHRLMNANFKB1PMP22MEN1 | |
| SCHEMBL8325849 | 0.86 | AKR1B1 (0.50) | TSHRMEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL7148017 | 0.83 | CES1 (0.44) | TSHRMEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL7148023 | 0.83 | CES1 (0.44) | TSHRMEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL7148020 | 0.83 | CES1 (0.44) | TSHRMEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL4449633 | 0.78 | — | — | |
| SCHEMBL5640537 | 0.78 | KDM1A (0.53) | PTPN1BLM | |
| SCHEMBL5640545 | 0.78 | KDM1A (0.53) | PTPN1BLM | |
| SCHEMBL10416148 | 0.78 | MEN1 (0.44) | TSHRMEN1KMT2A | |
| SCHEMBL5640541 | 0.78 | KDM1A (0.53) | PTPN1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227895-A1 | Fire retardant vinyl chloride-based resin composition and molded article thereof | MITSUBISHI PLASTICS, INC. (JP) | 2008-09-18 | — | — | US | disclosed |
| US-20060014874-A1 | Flame-resistant vinyl chlorride based resin composition and formed product therefrom | MITSUBISHI PLASTICS, INC. (JP) | 2006-01-19 | — | — | US | disclosed |