Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148017 | 0.93 | CES1 (0.44) | AKR1B1MEN1KMT2AFAAHTP53 | |
| SCHEMBL7148023 | 0.93 | CES1 (0.44) | AKR1B1MEN1KMT2AFAAHTP53 | |
| SCHEMBL7148020 | 0.93 | CES1 (0.44) | AKR1B1MEN1KMT2AFAAHTP53 | |
| SCHEMBL5078045 | 0.86 | TSHR (0.41) | MEN1KMT2AFAAHTP53CYP1A2 | |
| SCHEMBL11876598 | 0.84 | FAAH (0.50) | AKR1B1MEN1KMT2AFAAHTP53 | |
| SCHEMBL11876603 | 0.84 | FAAH (0.50) | AKR1B1MEN1KMT2AFAAHTP53 | |
| SCHEMBL2076983 | 0.84 | — | — | |
| SCHEMBL3399798 | 0.84 | — | — | |
| SCHEMBL2191702 | 0.84 | — | — | |
| SCHEMBL12812666 | 0.83 | FAAH (0.53) | MEN1KMT2AFAAHTP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005146-A | IMPROVED ADHESION PROMOTERS FOR LATEX PAINTS | EASTMAN CHEMICAL COMPANY (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0953019-A1 | STABILIZED NON-POLYMERIC ACETOACETATE ESTERS THAT PROMOTE ADHESION TO METALLIC AND OXIDIZED SUBSTRATES | EASTMAN CHEMICAL COMPANY (US) | 1999-11-03 | — | — | EP | disclosed |
| US-5913970-A | NONPOLYMERIC ENAMINE ADDED TO AN AQUEOUS DISPERSION POLYMER IN THE PRESENCE OF OTHER CONVENTIONAL PAINT ADDITIVES | EASTMAN CHEMICAL COMPANY (US) | 1999-06-22 | — | — | US | disclosed |
| WO-1998031753-A1 | STABILIZED NON-POLYMERIC ACETOACETATE ESTERS THAT PROMOTE ADHESION TO METALLIC AND OXIDIZED SUBSTRATES | EASTMAN CHEMICAL COMPANY (US) | 1998-07-23 | — | — | WO | disclosed |