Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3999593 | 0.93 | PTGS1 (0.33) | KDM4EMAPTPTGS1PTGS2 | |
| SCHEMBL7188586 | 0.91 | SLC6A4 (0.33) | ALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL273189 | 0.90 | SLC6A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL3401092 | 0.87 | DRD2 (0.30) | — | |
| SCHEMBL4000317 | 0.87 | ALDH1A1 (0.33) | ALDH1A1CYP2A6KDM4EMAPTPTGS1 | |
| SCHEMBL4002684 | 0.86 | PDCD1 (0.33) | ALDH1A1 | |
| SCHEMBL5582114 | 0.82 | SLC6A4 (0.34) | — | |
| Hydrochloric Acid SCHEMBL272443 | 0.81 | SLC6A4 (0.34) | — | |
| Hydrochloric Acid SCHEMBL1024023 | 0.80 | — | — | |
| SCHEMBL4006349 | 0.80 | PTGS1 (0.35) | ALDH1A1CYP2A6KDM4EMAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358381-B2 | Racemoselective preparation of bridged metallocene complexes having unsubstituted or 2-substituted indenyl ligands | BASELL POLYOLEFINE GMBH (DE) | 2008-04-15 | — | — | US | disclosed |
| US-20060111527-A1 | Racemoselective preparation of bridged metallocene complexes having unsubstituted or 2-substituted indenyl ligands | EQUISTAR CHEMICALS, LP | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111527-A1 | Racemoselective preparation of bridged metallocene complexes having unsubstituted or 2-substituted indenyl ligands | ITPA, IMPA1, INTS9 | ALDH1A1 888/4885CYP2A6 1577/4885KDM4E 4291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.