SCHEMBL5078484

SCHEMBL5078484

O=C(c1ccc(O)cc1)c1cc(Oc2ccccc2)cc(Oc2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 5/20 0.61
LTA4H P09960 1/20 0.57
NR1H2 P55055 1/20 0.57
BAX Q07812 1/20 0.57
MEN1 O00255 2/20 0.55
RAB9A P51151 2/20 0.55
KMT2A Q03164 2/20 0.55
LMNA P02545 2/20 0.55
MAPT P10636 2/20 0.55
NPC1 O15118 1/20 0.53
ESR1 P03372 1/20 0.52
ESR2 Q92731 1/20 0.52
PKM P14618 1/20 0.52
HPGD P15428 1/20 0.52
HTT P42858 1/20 0.52
AKR1C3 P42330 1/20 0.51
POLB P06746 1/20 0.51
STS P08842 1/20 0.51
PARP10 Q53GL7 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10669290 0.89 SRD5A2 (0.75) SRD5A2LTA4HNR1H2BAXMEN1
SCHEMBL19406167 0.87 SRD5A2 (0.72) SRD5A2LTA4HNR1H2BAXMEN1
SCHEMBL24421578 0.85 SRD5A2 (0.69) SRD5A2LTA4HNR1H2BAXMEN1
SCHEMBL7938036 0.85 SRD5A2 (0.69) SRD5A2LTA4HNR1H2BAXMEN1
SCHEMBL24421676 0.85 SRD5A2 (0.69) SRD5A2LTA4HNR1H2BAXMEN1
SCHEMBL18401385 0.85 SRD5A2 (0.69) SRD5A2LTA4HNR1H2BAXMEN1
SCHEMBL10974054 0.85 AKR1C3 (0.64) SRD5A2LTA4HNR1H2BAXMEN1
SCHEMBL19317526 0.83 SRD5A2 (0.78) SRD5A2AKR1C3POLBPARP10
SCHEMBL5073345 0.83 SRD5A2 (0.62) SRD5A2LTA4HMEN1RAB9AKMT2A
SCHEMBL1082112 0.81 SRD5A2 (0.88) SRD5A2LTA4HNR1H2BAXAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1359176-B1 Polycarbonates, polyestercarbonates and polyesters having specific branched endgroups BAYER MATERIALSCIENCE AG (DE) 2008-08-27 EP disclosed
US-6825312-B2 POLYCARBONATESTER COPOLYMER MOLDING MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 2004-11-30 US disclosed
US-20040030090-A1 Polycarbonates, polyester carbonates and polyesters with special branched terminal groups BAYER AKTIENGESELLSCHAFT (DE) 2004-02-12 US disclosed
EP-1359176-A2 Polycarbonates, polyestercarbonates and polyesters having specific branched endgroups Bayer Aktiengesellschaft (DE) 2003-11-05 EP disclosed