Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5470900 | 0.94 | CYP3A4 (0.43) | TDP1KMT2AMEN1CYP3A4CYP17A1 | |
| SCHEMBL5080857 | 0.91 | TDP1 (0.52) | TDP1KMT2AMEN1CYP3A4CYP17A1 | |
| SCHEMBL5475452 | 0.91 | KMT2A (0.41) | TDP1KMT2AMEN1CYP3A4CYP17A1 | |
| SCHEMBL5078693 | 0.89 | TDP1 (0.54) | TDP1KMT2AMEN1CYP3A4CYP17A1 | |
| SCHEMBL5080855 | 0.82 | KMT2A (0.42) | TDP1KMT2AMEN1CYP3A4CYP17A1 | |
| SCHEMBL5084688 | 0.74 | ALDH1A1 (0.31) | TDP1CYP3A4ALDH1A1HPGDESR2 | |
| SCHEMBL5082259 | 0.74 | TDP1 (0.70) | TDP1KMT2AMEN1CYP3A4CYP17A1 | |
| SCHEMBL5703601 | 0.74 | PTK2 (0.40) | — | |
| SCHEMBL5832862 | 0.74 | PTK2 (0.37) | TDP1CYP3A4ALOX15SMN1; SMN2TP53 | |
| SCHEMBL5080918 | 0.74 | NOS1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1462471-B1 | Dielectric films and materials therefor | DAICEL CHEM (JP) | 2008-07-30 | — | — | EP | disclosed |
| US-7186454-B2 | Dielectric films and materials therefor | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-06 | — | — | US | disclosed |
| EP-1681284-A1 | AROMATIC POLYAMINE DERIVATIVE | Daicel Chemical Industries, Ltd. (JP) | 2006-07-19 | — | — | EP | disclosed |
| EP-1462471-A1 | Dielectric films and materials thereof | Daicel Chemical Industries, Ltd. (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-20040175858-A1 | Dielectric films and materials therefor | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2004-09-09 | — | — | US | disclosed |