Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.35 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250087 | 0.89 | HTT (0.45) | RECQLGLAHPGDTSHRMAPK1 | |
| Sulfuric Acid SCHEMBL5078787 | 0.87 | LSS (0.39) | LSSAPAF1HSP90AA1RAD52DNM1 | |
| SCHEMBL2995385 | 0.86 | RECQL (0.47) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL4665831 | 0.86 | RECQL (0.47) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL11290328 | 0.86 | RECQL (0.47) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL10588897 | 0.86 | RECQL (0.47) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL6708024 | 0.86 | RECQL (0.47) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL11291479 | 0.84 | RECQL (0.44) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL29165751 | 0.83 | RECQL (0.44) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL28813277 | 0.83 | RECQL (0.44) | RECQLGLAHPGDTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487955-B1 | AMMONIUM NITRILES AND THE USE THEREOF AS HYDROPHOBIC BLEACHING ACTIVATORS | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2008-05-21 | — | — | EP | disclosed |
| US-7015185-B2 | Ammonium nitriles and the use thereof as hydrophobic bleaching activators | CLARIANT GMBH (DE) | 2006-03-21 | — | — | US | disclosed |
| US-20040266644-A1 | Ammonium nitriles and the use thereof as hydrophobic bleaching activators | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2004-12-30 | — | — | US | disclosed |
| EP-1487955-A1 | AMMONIUM NITRILES AND THE USE THEREOF AS HYDROPHOBIC BLEACHING ACTIVATORS | Clariant GmbH (DE) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003078561-A1 | AMMONIUM NITRILES AND THE USE THEREOF AS HYDROPHOBIC BLEACHING ACTIVATORS | CLARIANT GMBH (DE) | 2003-09-25 | — | — | WO | disclosed |