Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 11/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28813277 | 1.00 | RECQL (0.44) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL27780849 | 0.96 | RECQL (0.44) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL28881714 | 0.94 | RECQL (0.41) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL6708024 | 0.92 | RECQL (0.47) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL2995385 | 0.92 | RECQL (0.47) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL4665831 | 0.92 | RECQL (0.47) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL10588897 | 0.92 | RECQL (0.47) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL11290328 | 0.92 | RECQL (0.47) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL30954840 | 0.92 | DNM1 (0.44) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL29281610 | 0.92 | DNM1 (0.44) | RECQLGLAHPGDTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355290-A | Hair coloring composition for reducing color loss | 路博润先进材料公司 | 2024-01-05 | — | — | CN | disclosed |