Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 10/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665831 | 1.00 | RECQL (0.47) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL10588897 | 1.00 | RECQL (0.47) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL11290328 | 1.00 | RECQL (0.47) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL2995385 | 1.00 | RECQL (0.47) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL11291479 | 0.98 | RECQL (0.44) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL29165751 | 0.92 | RECQL (0.44) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL27780849 | 0.92 | RECQL (0.44) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL28813277 | 0.92 | RECQL (0.44) | RECQLGLAHPGDTSHRMAPK1 | |
| Tributylmethylammonium SCHEMBL306587 | 0.92 | RECQL (0.41) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL6668543 | 0.91 | DNM1 (0.47) | RECQLGLAHPGDTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833463-B2 | Transesterification using phase transfer catalysts | PTC ORGANICS, INC. | 2004-12-21 | — | — | US | disclosed |
| US-20040167343-A1 | Transesterification using phase transfer catalysts | PTC ORGANICS, INC. | 2004-08-26 | — | — | US | disclosed |
| WO-2003020782-A2 | TRANSESTERIFICATION USING PHASE TRANSFER CATALYSTS | PTC ORGANICS, INC. (US) | 2003-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167343-A1 | Transesterification using phase transfer catalysts | CETP, LIPC, DGAT2 | RECQL 1759/4885GLA 1224/4885HPGD 1407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.