Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | AHR | P35869 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | DHODH | Q02127 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748719 | 0.87 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTHTTALDH1A1RAB9A | |
| SCHEMBL9494555 | 0.85 | SMN1; SMN2 (0.77) | SMN1; SMN2MAPTHTTALDH1A1RAB9A | |
| SCHEMBL7272538 | 0.84 | KDM4E (0.66) | SMN1; SMN2MAPTHTTALDH1A1RAB9A | |
| SCHEMBL13134029 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTHTTALDH1A1RAB9A | |
| SCHEMBL30240978 | 0.80 | SYK (0.57) | SMN1; SMN2MAPTHTTALDH1A1RAB9A | |
| SCHEMBL538171 | 0.80 | KMT2A (0.51) | SMN1; SMN2MAPTHTTALDH1A1RAB9A | |
| SCHEMBL4642709 | 0.79 | CLCN2 (0.59) | MAPTALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL7982557 | 0.79 | NPC1 (0.52) | MAPTHTTALDH1A1RAB9AHPGD | |
| SCHEMBL479805 | 0.78 | DHODH (0.76) | SMN1; SMN2MAPTHTTALDH1A1RAB9A | |
| SCHEMBL29898269 | 0.78 | RAB9A (1.00) | SMN1; SMN2MAPTHTTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105939998-A | Heteroaryl compounds as btk inhibitors and uses thereof | 默克专利有限公司 | 2016-09-14 | — | — | CN | disclosed |
| US-20080132505-A1 | Combination Of Cb2 Modulators And Pde4 Inhibitors For Use In Medicine | GLAXO GROUP LIMITED | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132505-A1 | Combination Of Cb2 Modulators And Pde4 Inhibitors For Use In Medicine | CNR2, CNR1, PDE4A | SMN1; SMN2 3540/4885MAPT 3180/4885HTT 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.