SCHEMBL5079167

SCHEMBL5079167

OOCc1ccc(Cl)cc1Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.64
CYP1A2 P05177 3/20 0.52
CYP2C9 P11712 3/20 0.52
CYP2C19 P33261 3/20 0.52
CYP3A4 P08684 2/20 0.52
MAPK1 P28482 1/20 0.52
NR4A2 P43354 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
NR4A1 P22736 1/20 0.47
NR4A3 Q92570 1/20 0.47
GAA P10253 1/20 0.47
HTT P42858 2/20 0.47
MRGPRX4 Q96LA9 1/20 0.46
CHRNB2 P17787 1/20 0.46
CHRNA4 P43681 1/20 0.46
GGPS1 O95749 1/20 0.46
CYP2D6 P10635 2/20 0.45
MAPT P10636 1/20 0.45
RECQL P46063 1/20 0.45
HDAC8 Q9BY41 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29984975 0.82 IDO1 (0.69) IDO1CYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL7888003 0.82 IDO1 (0.69) IDO1CYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL165560 0.82 IDO1 (0.69) IDO1CYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL11002124 0.79 IDO1 (0.60) IDO1CYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL11129339 0.78 IDO1 (0.64) IDO1CYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL11157965 0.78 IDO1 (0.64) IDO1CYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL1989190 0.78 IDO1 (0.64) IDO1CYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL1989192 0.78 IDO1 (0.64) IDO1CYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL9767549 0.78 IDO1 (1.00) IDO1CYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL2130970 0.78 IDO1 (0.64) IDO1CYP1A2CYP2C9CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1533108-B1 Pneumatic tire with built-in colored sealant layer and method of preparing said pneumatic tire GOODYEAR TIRE & RUBBER (US) 2012-09-26 EP claimed
EP-1457308-B1 Pneumatic tire having built-in sealant layer and preparation thereof GOODYEAR TIRE & RUBBER (US) 2008-10-01 EP claimed
EP-1721932-B1 Pneumatic tire with built-in sealant containing pre-hydrophobated silica GOODYEAR TIRE & RUBBER (US) 2008-08-13 EP claimed
EP-1033386-B1 Preparation of peroxide vulcanized rubber composition and articles having at least one component thereof GOODYEAR TIRE & RUBBER (US) 2006-08-02 EP claimed
CN-111675620-A Method for catalytic oxidation of toluene and derivatives thereof by metalloporphyrin 浙江工业大学 2020-09-18 CN disclosed
US-7811742-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2010-10-12 US disclosed
US-20080268372-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed
US-6828086-B2 For use in imaging material KONICA CORPORATION (JP) 2004-12-07 US disclosed
US-20030186180-A1 Water-based coating composition, infrared absorbing film, and photothermographic material by use thereof KONICA CORPORATION (JP) 2003-10-02 US disclosed
US-20020015925-A1 Image forming material KONICA CORPORATION (JP) 2002-02-07 US disclosed
US-6280917-B1 POLYMER HAVING AN ETHYLENICALLY UNSATURATED MONOMER UNIT CONTAINING AN ACTIVE METHYLENE GROUP AND AN ETHYLENICALLY UNSATURATED MONOMER UNIT SELECTED FROM METHACRYLIC ACID ESTER, ACRYLIC ACID ESTER, MALEIC ACID ESTER AND DIENE DERIVATIVE KONICA CORPORATION (JP) 2001-08-28 US disclosed
EP-0000507-B1 PROCESS FOR THE PRODUCTION OF HYDROGELS IN THE FORM OF SPHERICALLY SHAPED BEADS WITH LARGER DIAMETERS CIBA-GEIGY AG (CH) 1982-09-29 EP disclosed