SCHEMBL9767549

SCHEMBL9767549

NOCc1ccc(Cl)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 12/20 1.00
CYP3A4 P08684 3/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
MAPK1 P28482 1/20 0.52
CYP2C19 P33261 1/20 0.52
AGXT P21549 4/20 0.50
CHRNB2 P17787 1/20 0.50
CHRNA4 P43681 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
NR4A2 P43354 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1715908 0.98 IDO1 (1.00) IDO1CYP3A4CYP1A2CYP2C9MAPK1
Hydrochloric Acid SCHEMBL1715890 0.98 IDO1 (1.00) IDO1CYP3A4CYP1A2CYP2C9MAPK1
SCHEMBL4019593 0.83 IDO1 (0.70) IDO1CYP3A4AGXT
SCHEMBL29984975 0.82 IDO1 (0.69) IDO1CYP3A4CYP1A2CYP2C9MAPK1
SCHEMBL165560 0.82 IDO1 (0.69) IDO1CYP3A4CYP1A2CYP2C9MAPK1
SCHEMBL7888003 0.82 IDO1 (0.69) IDO1CYP3A4CYP1A2CYP2C9MAPK1
SCHEMBL12229609 0.81 IDO1 (0.68) IDO1CYP3A4MAPK1AGXTHTT
Hydrochloric Acid SCHEMBL2514135 0.81 IDO1 (0.71) IDO1CYP3A4AGXT
SCHEMBL25394603 0.79 IDO1 (0.66) IDO1AGXT
SCHEMBL17928811 0.79 IDO1 (0.66) IDO1MAPK1AGXTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023166067-A1 MICROBIOCIDAL PYRIDAZINONE AMIDE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-09-07 WO disclosed
CN-103102284-A Preparation of 4-trifluoromethyl-2, 6-dinitrobenzene salicylaldoxime derivative and its application in anticancer therapeutic drugs NANJING UNIVERSITY OF TECHNOLOGY 2013-05-15 CN disclosed
WO-2013067519-A2 INSECT AND TICK G-COUPLED RECEPTORS USEFUL AS TARGETS FOR INSECTICIDES AND COMPOUNDS AND REAGENTS IDENTIFIED USING THE SAME PURDUE RESEARCH FOUNDATION (US) 2013-05-10 WO disclosed
US-5053070-A PYRIMIDINE DERIVATIVES, PREPARATION PROCESSES THEREOF, HERBICIDE CONTAINING THE SAME, AND HERBICIDAL COMPOSITIONS CONTAINING THE SAME ALONG WITH OTHER ACTIVE INGREDIENT MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1991-10-01 US disclosed
US-4986846-A PRE-AND POSTEMERGENCE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1991-01-22 US disclosed
EP-0374839-A1 2-(4,6-Dimethoxy-2-pyrimidinyloxy)benzaldoximes, preparation processes thereof, herbicides containing the same, and herbicidal compositions containing the same along with other active ingredients MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-06-27 EP disclosed
US-4517183-A COMBATING DISEASES WITH WEAKNESS OF IMMUNE SYSTEMS BOEHRINGER MANNHEIM GMBH (DE) 1985-05-14 US disclosed
EP-0014976-B1 N-SUBSTITUTED 2-CYANAZIRIDINES, METHODS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM, CORRESPONDINGLY SUBSTITUTED AZIRIDINE-2-CARBONAMIDES AND THEIR PREPARATION Roche Diagnostics GmbH (DE) 1982-04-07 EP disclosed
US-4293715-A FUNGICIDES, BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1981-10-06 US disclosed