Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | NOS2 | P35228 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056010 | 0.80 | SLC6A2 (0.61) | PPARGSLC6A2SLC6A4NOS2CYP2D6 | |
| Oxalic Acid SCHEMBL3203 | 0.79 | SLC6A2 (0.49) | PPARGSLC6A2SLC6A4SLC6A3KCNK2 | |
| SCHEMBL5079373 | 0.72 | SLC6A4 (0.56) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5080428 | 0.72 | SLC6A2 (0.51) | PPARGSLC6A2SLC6A4SLC6A3KCNK2 | |
| SCHEMBL17278135 | 0.72 | SLC7A5 (0.65) | PPARGSLC6A2SLC6A4SLC6A3KCNK2 | |
| Oxalic Acid SCHEMBL7317717 | 0.72 | SLC6A2 (0.60) | PPARGSLC6A2SLC6A4NOS2CYP2D6 | |
| SCHEMBL19668486 | 0.70 | NOS2 (0.50) | PPARGSLC6A2SLC6A4NOS2SLC6A3 | |
| SCHEMBL23521648 | 0.68 | SLC6A2 (0.38) | SLC6A2SLC6A4NOS2CYP2D6SLC6A3 | |
| SCHEMBL21742901 | 0.68 | SLC6A2 (0.38) | SLC6A2SLC6A4NOS2CYP2D6SLC6A3 | |
| Oxalic Acid SCHEMBL4936002 | 0.68 | SLC6A2 (0.59) | SLC6A2SLC6A4NOS2CYP2D6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744474-A | ADMINISTERING VENLAFAXINE OR DULOXETINE; TREATING STRESS, URGE AND/OR NOCTURNAL URINARY INCONTINENCE | ELI LILLY AND COMPANY (US) | 1998-04-28 | — | — | US | disclosed |