Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935732 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL6908748 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL11608975 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL25267333 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL6908797 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL23530251 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL6914870 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL4439197 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL8374916 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL6913124 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877109-A | Catalyst for the gas-phase polymerisation of conjugated dienes | BAYER AG (DE) | 1999-03-02 | — | — | US | claimed |
| EP-1972644-B1 | METHOD FOR PRODUCING CIS-1,4 DIENE RUBBER, CATALYST, RUBBER | OTKRYTOE AKTSIONERNOE OBSCHESTVO EFREMOVSKY ZD SINT KAUCHUKA (RU) | 2013-03-06 | — | — | EP | disclosed |
| EP-1972644-A1 | METHOD FOR PRODUCING CIS-1,4 DIENE RUBBER, CATALYST, RUBBER | Otkrytoe Aktsionernoe Obschestvo 'Efremovsky Zavod Sinteticheskogo Kauchuka' (RU) | 2008-09-24 | — | — | EP | disclosed |
| US-20040167276-A1 | Block copolymer based on conjugated diolefins and polar monomers | ARLANXEO DEUTSCHLAND GMBH (DE) | 2004-08-26 | — | — | US | disclosed |
| US-6734257-B2 | SUCH AS ADDITION-CONDENSATION POLYMERS OF BUTADIENE AND E-CAPROLACTONE; HIGH CIS-1,4 CONTENT IN THE POLYDIENE BLOCK; USE TO IMPART COMPATIBILITY IN VULCANIZATES FOR TIRES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-05-11 | — | — | US | disclosed |
| US-20040030071-A1 | Method for polymerizing conjugated diolefins (dienes) with catalysts of rare earths in the presence of vinyl aromatic solvents | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-12 | — | — | US | disclosed |
| EP-0903357-B1 | Synthesis of 1,4-trans-polybutadiene using a lanthanide organic acid salt catalyst | BRIDGESTONE CORP (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-20030134999-A1 | Method for polymerizing conjugated diolefins (dienes) with rare earth catalysts in the presence of vinylaromatic solvents | WINDISCH HEIKE (DE) | 2003-07-17 | — | — | US | disclosed |
| US-6576727-B1 | Rare earth alcoholate and carboxylate, organoaluminum compound, and Lewis acid; flowability | BAYER AKTIENGESELLSCHAFT (DE) | 2003-06-10 | — | — | US | disclosed |
| US-20020183467-A1 | Block copolymer based on conjugated diolefins and polar monomers | ARLANXEO DEUTSCHLAND GMBH (DE) | 2002-12-05 | — | — | US | disclosed |
| WO-2000018812-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF DIENES, CATALYST OBTAINED THEREFROM, AND PROCESS FOR THE PREPARATION OF POLYDIENES USING THE SAME | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-04-06 | — | — | WO | disclosed |
| US-6018007-A | POLYMERIZING BUTADIENE MONOMERS IN THE PRESENCE OF A CATALYST SYSTEM CONSISTING ESSENTIALLY OF: (A) AN ALKYLLITHIUM CATALYST; (B) AN ORGANIC ACID SALT OF LANTHANIDE SERIES ELEMENT; OPTIONALLY A DIETHYLZINC AND/OR A POLAR DILUENT | BRIDGESTONE CORPORATION (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0964008-A1 | Organo zinc and rare earth catalyst system in the polymerization of conjugated dienes | Bridgestone Corporation (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5914377-A | Method for the production of diene rubbers in the gas phase | BAYER AG (DE) | 1999-06-22 | — | — | US | disclosed |
| US-5908904-A | RARE EARTH COMPOUND; TRIALKYLALUMINUM, DIALKYLALUMINUM HYDRIDE OR ALUMOXANE; ANOTHER LEWIS ACID; INERT, PARTICULATE INORGANIC SOLID WITH A SPECIFIC SURFACE OF GREATER THAN 10 M.SUP.2 /G (BET) AND A PORE VOLUME OF 0.3 TO 15 ML/G. | BAYER AG (DE) | 1999-06-01 | — | — | US | disclosed |
| EP-0903357-A1 | Synthesis of 1,4-trans-polybutadiene using a lanthanide organic acid salt catalyst | Bridgestone Corporation (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5877109-A | Catalyst for the gas-phase polymerisation of conjugated dienes | BAYER AG (DE) | 1999-03-02 | — | — | US | disclosed |
| US-5858903-A | POWDERED COORDINATION CATALYST OF AN ORGANIC RARE EARTH COMPOUND AND AN ORGANOALUMINUM COMPOUND; SOLVENT-FREE; POLLUTION CONTROL; POLYBUTADIENE AND POLYISOPRENE SYNTHETIC RUBBERS; TIRES | BAYER AG (DE) | 1999-01-12 | — | — | US | disclosed |
| US-4260707-A | Solution polymerization of conjugated dienes | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4242232-A | Catalyst and its preparation and use for the solution polymerization of conjugated dienes | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |