Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6916650 | 1.00 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL6915157 | 1.00 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL6914897 | 0.97 | CES2 (0.50) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL11608975 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL5079485 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL23530251 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL6914870 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL6908748 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL4439197 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL6913757 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6830704-B2 | Contains a Lewis acid metal salt and a compound having clathrating ability. | TOAGOSEI CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| US-20030135016-A1 | Contains a Lewis acid metal salt and a compound having clathrating ability. | TOAGOSEI CO., LTD. | 2003-07-17 | — | — | US | disclosed |
| US-6547985-B1 | Adhesive mixture | TOGOSEI CO., LTD. (JP) | 2003-04-15 | — | — | US | disclosed |
| US-5512319-A | COATING FABRIC WITH SILICONE SURFACTANT DISSOLVED IN WATER, EXPANDING POLYURETHANE FOAMING MIXTURE IN CONTACT WITH COATED FABRIC | BASF CORPORATION (US) | 1996-04-30 | — | — | US | disclosed |
| US-4764543-A | Microcellular foamed or reaction injection molded polyurethane/polyureas employing amine terminated polymers and diamine chain extenders | THE DOW CHEMICAL COMPANY (US) | 1988-08-16 | — | — | US | disclosed |
| US-4757095-A | Polyurethane-polyurea composition comprising reaction product of a mixture of diphenylmethane diisocyanate and uretonimine modified diisocyanate, polyol, with a lactone and a lactam, an alkane diol, and catalyst | BASF CORPORATION (US) | 1988-07-12 | — | — | US | disclosed |
| US-4633002-A | Aminofunctional polysiloxane compounds and method of preparation therefor | Piskoti, Charles (US) | 1986-12-30 | — | — | US | disclosed |
| US-4596685-A | Reacting polyisocyanate, polyols, and oxyethylated amine | BASF CORPORATION (US) | 1986-06-24 | — | — | US | disclosed |
| US-4588542-A | INJECTION, CURING A FOAMABLE POLYURETHANE IN TIRE MOLD | G. P. PLASTICS, INC. (US) | 1986-05-13 | — | — | US | disclosed |
| EP-0107108-B1 | ALKYLATED VICINAL TOLUENEDIAMINES AND THEIR USE AS CHAIN EXTENDERS IN THE PREPARATION OF POLYURETHANE-POLYUREA ELASTOMERS | BASF Corporation (US) | 1986-03-05 | — | — | EP | disclosed |
| EP-0045413-A1 | Flexible polyurethane foam compositions and methods for the preparation | BASF WYANDOTTE CORPORATION (US) | 1982-02-10 | — | — | EP | disclosed |
| US-4235765-A | SURFACE COATINGS FOR ATHLETIC ARENAS | BASF WYANDOTTE CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |
| US-4232127-A | POLYMERIZATION CATALYSTS, CONDENSATION POLYMERIZATION | BASF WYANDOTTE CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| US-4210728-A | Preparation of high resiliency polyurethane foams | BASF WYANDOTTE CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |
| US-4175155-A | GLASS FIBER MAT WITH FOAMED, CURED POLYURETHANE RESIN | GAF CORPORATION (US) | 1979-11-20 | — | — | US | disclosed |
| EP-0003954-A1 | Reactive polyol compositions and high resiliency polyurethane foams obtained by using these compositions | BASF WYANDOTTE CORPORATION (US) | 1979-09-19 | — | — | EP | disclosed |
| US-3994837-A | Urethane-modified carbodiimide-isocynurate foams prepared from TDI-rich isocyanates | BASF WYANDOTTE CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
| US-3994839-A | Urethane modified carbodiimide foams derived from flame retardant polyols | BASF WYANDOTTE CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
| US-3981828-A | ISOCYANATE TRIMERIZATION CATALYSTS | BASF WYANDOTTE CORPORATION (US) | 1976-09-21 | — | — | US | disclosed |
| US-3969288-A | Carbodiimide-isocyanurate foams prepared from acid-modified toluene diisocyanate | BASF WYANDOTTE CORPORATION (US) | 1976-07-13 | — | — | US | disclosed |