Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078856 | 0.88 | ALDH1A1 (0.47) | ALDH1A1GAATSHRMAPK1KMT2A | |
| SCHEMBL5082925 | 0.88 | ALDH1A1 (0.50) | ALDH1A1GAATSHRMAPK1KMT2A | |
| SCHEMBL5082919 | 0.86 | ALDH1A1 (0.45) | ALDH1A1GAATSHRMAPK1KMT2A | |
| SCHEMBL5079623 | 0.81 | ALDH1A1 (0.53) | ALDH1A1GAATSHRMAPK1KMT2A | |
| SCHEMBL5077042 | 0.80 | ALDH1A1 (0.51) | ALDH1A1GAATSHRKMT2AMAPT | |
| SCHEMBL5080642 | 0.80 | ALDH1A1 (0.51) | ALDH1A1TSHRKMT2AMAPTKDM4E | |
| SCHEMBL5080682 | 0.80 | ALDH1A1 (0.51) | ALDH1A1TSHRKMT2AMAPTKDM4E | |
| SCHEMBL4628659 | 0.75 | TSHR (0.61) | ALDH1A1TSHRMAPK1KMT2AMAPT | |
| SCHEMBL827863 | 0.74 | TSHR (0.70) | ALDH1A1TSHRMAPK1KMT2AMAPT | |
| SCHEMBL9045800 | 0.73 | NPSR1 (0.46) | ALDH1A1GAATSHRMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1871266-B | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE SPA | 2012-05-09 | — | — | CN | disclosed |
| US-7371802-B2 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2008-05-13 | — | — | US | disclosed |
| US-20070106039-A1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2007-05-10 | — | — | US | disclosed |