SCHEMBL5079648

SCHEMBL5079648

[O]CC#Cc1ccc(Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.46
KCNH2 Q12809 4/20 0.41
CYP2A6 P11509 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ACACB O00763 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.37
ALDH1A1 P00352 1/20 0.36
GRM5 P41594 1/20 0.36
DRD2 P14416 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9484463 0.78 LMNA (0.47) LMNAKCNH2CYP2A6MEN1KMT2A
SCHEMBL12325023 0.76 LMNA (0.46) LMNAKCNH2CYP2A6MEN1KMT2A
SCHEMBL5079380 0.76 LMNA (0.46) LMNAKCNH2CYP2A6MEN1KMT2A
SCHEMBL16380473 0.76 KCNH2 (0.53) LMNAKCNH2CYP2A6MEN1KMT2A
SCHEMBL5079375 0.76 LMNA (0.46) LMNAKCNH2CYP2A6MEN1KMT2A
SCHEMBL2432676 0.76 LMNA (0.46) LMNAKCNH2CYP2A6MEN1KMT2A
SCHEMBL1746428 0.76 LMNA (0.50) LMNAKCNH2CYP2A6MEN1KMT2A
SCHEMBL2080824 0.76 CYP2C19 (0.60) LMNAKCNH2CYP2A6GRM5DRD2
SCHEMBL20015814 0.76 LMNA (0.57) LMNAKCNH2CYP2A6ACACBPTGDR2
SCHEMBL719360 0.76 LMNA (0.57) LMNAKCNH2CYP2A6ACACBPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP disclosed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO disclosed
US-5463062-A Inhibitors of glucose-6-phosphatase system HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT LMNA 4661/4885KCNH2 3103/4885CYP2A6 204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.