Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20015814 | 1.00 | LMNA (0.57) | LMNACYP2A6KCNH2GRM5APP | |
| Charcoal, Activated SCHEMBL31286310 | 0.97 | KCNH2 (0.54) | LMNACYP2A6KCNH2GRM5APP | |
| SCHEMBL717633 | 0.88 | APP (0.67) | LMNACYP2A6KCNH2GRM5APP | |
| SCHEMBL29001498 | 0.86 | APP (0.47) | LMNACYP2A6KCNH2GRM5APP | |
| SCHEMBL8618771 | 0.86 | APP (0.74) | LMNACYP2A6KCNH2GRM5APP | |
| SCHEMBL28629285 | 0.86 | GRM5 (0.52) | LMNACYP2A6KCNH2GRM5ACACB | |
| SCHEMBL6045133 | 0.86 | GRM5 (0.47) | LMNACYP2A6KCNH2GRM5APP | |
| SCHEMBL4461464 | 0.86 | KCNH2 (0.47) | LMNACYP2A6KCNH2GRM5APP | |
| SCHEMBL2879214 | 0.84 | LMNA (0.47) | LMNACYP2A6KCNH2GRM5APP | |
| SCHEMBL8093298 | 0.84 | KCNH2 (0.45) | LMNACYP2A6KCNH2GRM5APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874421-A | Method for synthesizing 1,1' -biisoquinoline derivative from 2, 2-dimethyl-4, 5-diaryl-2H-imidazole | 桂林理工大学 | 2023-10-13 | — | — | CN | claimed |
| CN-116283962-A | Method for synthesizing imidazo [5,1-a ] isoquinoline derivatives through C-H activation/cyclization reaction | 桂林理工大学 | 2023-06-23 | — | — | CN | claimed |
| US-7595413-B2 | Phosphine-substituted vinyl containing metallocene catalyst, preparation process and the application of the same | PETROCHINA COMPANY LIMITED (CN) | 2009-09-29 | — | — | US | claimed |
| US-20080194854-A1 | Phosphine-substituted vinyl containing metallocene catlyst, preparation process and the application of the same | PETROCHINA COMPANY LIMITED (CN) | 2008-08-14 | — | — | US | claimed |
| US-4070333-A | AROMATIZATION CATALYST, ADDITION POLYMERIZATION | HERCULES INCORPORATED (US) | 1978-01-24 | — | — | US | claimed |
| CN-119346167-A | Catalytic system and method for synthesizing diaryl acetylene from calcium carbide and iodo aromatic hydrocarbon | 石河子大学 | 2025-01-24 | — | — | CN | disclosed |
| CN-119192123-A | Preparation method of polysubstituted isocoumarin compound | 厦门医学院 | 2024-12-27 | — | — | CN | disclosed |
| CN-118496244-A | Rhodium catalyzed C-H cyclization construction of pyridophenothiazine/oxa/selenazinium salt organic single molecule white light material | 重庆大学 | 2024-08-16 | — | — | CN | disclosed |
| CN-116120549-B | Method for preparing phthalonitrile resin by using 1, 2-disubstituted o-carborane monomer | 大连理工大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-118420533-A | Method for synthesizing isoquinolinone by carbonylation of aryl alkyne and hydroxylamine | 中国科学技术大学 | 2024-08-02 | — | — | CN | disclosed |
| CN-118324603-A | Method for synthesizing chrysene derivatives through palladium-catalyzed cycloaromatization reaction | 湖南师范大学 | 2024-07-12 | — | — | CN | disclosed |
| CN-117945820-A | Method for synthesizing alpha, beta-unsaturated aldehyde compound by copper catalysis | 江苏海洋大学 | 2024-04-30 | — | — | CN | disclosed |
| EP-0000385-A1 | Thermosetting compositions based on polyarylacetylenes and substituted polyphenylene oxides and resins obtained by curing them | HERCULES INCORPORATED (US) | 1979-01-24 | — | — | EP | disclosed |
| US-4097460-A | DIPHENYLACETYLENE, DIPHENYLBUTADIYNE, MOLDING MATERIALS FOR HIGH TEMPERATURE APPLICATIONS | HERCULES INCORPORATED (US) | 1978-06-27 | — | — | US | disclosed |
| US-4070333-A | AROMATIZATION CATALYST, ADDITION POLYMERIZATION | HERCULES INCORPORATED (US) | 1978-01-24 | — | — | US | disclosed |
| US-4026859-A | AROMATIZATION CATALYST | HERCULES INCORPORATED (US) | 1977-05-31 | — | — | US | disclosed |
| US-4026860-A | AROMATIZATION CATALYST | HERCULES INCORPORATED (US) | 1977-05-31 | — | — | US | disclosed |
| US-4026861-A | AROMATIZATION CATALYST | HERCULES INCORPORATED (US) | 1977-05-31 | — | — | US | disclosed |
| US-3993711-A | THERMOSETTING RESINS; COUPLING AGENTS; CARBOXYLATED PREPOLYMER | HERCULES INCORPORATED (US) | 1976-11-23 | — | — | US | disclosed |
| US-3931093-A | CURING | HERCULES INCORPORATED (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194854-A1 | Phosphine-substituted vinyl containing metallocene catlyst, preparation process and the application of the same | PI4K2B, PI4K2A, CPNE4 | LMNA 3023/4885CYP2A6 2964/4885KCNH2 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.