SCHEMBL507968

SCHEMBL507968

O=c1[nH]c2ccccc2cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DAO P14920 15/20 1.00
DDO Q99489 5/20 1.00
BRD4 O60885 1/20 0.60
CHEK1 O14757 1/20 0.56
KDR P35968 1/20 0.56
GRIN2D O15399 1/20 0.54
GRIN3B O60391 1/20 0.54
GRIN1 Q05586 1/20 0.54
GRIN2A Q12879 1/20 0.54
GRIN2B Q13224 1/20 0.54
GRIN2C Q14957 1/20 0.54
GRIN3A Q8TCU5 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30077634 1.00 DAO (1.00) DAODDOBRD4CHEK1KDR
SCHEMBL3237176 0.98 DAO (0.96) DAODDOBRD4CHEK1KDR
Sulfuric Acid SCHEMBL1467316 0.93 DAO (0.86) DAODDOBRD4CHEK1KDR
SCHEMBL8873240 0.88 DAO (0.79) DAODDOBRD4CHEK1KDR
SCHEMBL17175695 0.78 DAO (0.64) DAODDOGRIN2DGRIN3BGRIN1
SCHEMBL2639080 0.76 DAO (0.61) DAODDOGRIN2DGRIN3BGRIN1
SCHEMBL1367711 0.76 DAO (0.61) DAODDOBRD4CHEK1KDR
SCHEMBL7341095 0.76 DAO (0.61) DAODDOGRIN2DGRIN3BGRIN1
SCHEMBL1625559 0.75 DAO (0.60) DAODDOBRD4CHEK1KDR
SCHEMBL545302 0.75 DAO (0.60) DAODDOBRD4CHEK1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 560 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4504712-A1 GPR35 MODULATORS AND USES THEREOF Crossignal Therapeutics, Inc. (US) 2025-02-12 EP claimed
CN-119137105-A GPR35 modulators and uses thereof 交信医药研发公司 2024-12-13 CN claimed
CN-118680838-A Freckle-removing and whitening compound and preparation method thereof 广州颜当家化妆品科技有限公司 2024-09-24 CN claimed
WO-2023196538-A1 GPR35 MODULATORS AND USES THEREOF CROSSIGNAL THERAPEUTICS, INC. (US) 2023-10-12 WO claimed
EP-3071634-B1 SELF-HEALING POLYMERIC COMPOSITION BATTELLE MEMORIAL INSTITUTE (US) 2023-08-30 EP claimed
CN-116589403-A 3-hydroxyquinoline-2-ketone compound and synthetic method and application thereof 浙江工业大学 2023-08-15 CN claimed
EP-2802871-B1 CHARACTERIZATION OF SUBVISIBLE PARTICLES USING A PARTICLE ANALYZER TAKEDA PHARMACEUTICALS CO (JP) 2022-07-27 EP claimed
US-10752606-B2 Methods for treating protozoan infections NEOCULI PTY LTD. (AU) 2020-08-25 US claimed
US-20200102287-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS NEOCULI PTY LTD (AU) 2020-04-02 US claimed
US-10562880-B2 Methods for treating protozoan infections NEOCULI PTY LTD. (AU) 2020-02-18 US claimed
WO-2009064291-A1 CYANOACRYLATE TISSUE ADHESIVES SPARTAN MEDICAL PRODUCTS, LLC (US) 2009-05-22 WO claimed
EP-1509236-A4 TREATMENT AND PREVENTION OF ABNORMAL SCAR FORMATION IN KELOIDS AND OTHER CUTANEOUS OR INTERNAL WOUNDS OR LESIONS CHILDREN S HOSPITAL LOS ANGELE (US) 2008-07-30 EP claimed
US-20070281360-A1 PROTEIN DETECTION AND QUANTITATION USING HYDROXYQUINOLONE DYES PIERCE BIOTECHNOLOGY, INC. (US) 2007-12-06 US claimed
EP-1509236-A2 TREATMENT AND PREVENTION OF ABNORMAL SCAR FORMATION IN KELOIDS AND OTHER CUTANEOUS OR INTERNAL WOUNDS OR LESIONS Children's Hospital of Los Angeles (US) 2005-03-02 EP claimed
WO-2004041155-A2 TREATMENT AND PREVENTION OF ABNORMAL SCAR FORMATION IN KELOIDS AND OTHER CUTANEOUS OR INTERNAL WOUNDS OR LESIONS CHILDREN'S HOSPITAL LOS ANGELES (US) 2004-05-21 WO claimed
US-20040043026-A1 Treatment and prevention of abnormal scar formation in keloids and other cutaneous or internal wounds or lesions NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-03-04 US claimed
US-20030162951-A1 Yellow disperse dye mixture DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-08-28 US claimed
EP-0752452-B1 Hydroxyquinolone-monoazo dyes, their preparation and use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-09-12 EP claimed
WO-2001047481-A1 COMPOSITION FOR THE TREATMENT OF DANDRUFF PHARMASKIN LTD. (IL) 2001-07-05 WO claimed
US-5760197-A YELLOW PIGMENT FOR DYEING TEXTILES DYSTAR JAPAN LTD. (JP) 1998-06-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200102287-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS DPM1, ABCB11, PIGS DAO 995/4885DDO 1823/4885BRD4 4083/4885
US-10562880-B2 Methods for treating protozoan infections DPM1, ABCB11, PIGS DAO 995/4885DDO 1823/4885BRD4 4083/4885
US-10752606-B2 Methods for treating protozoan infections DPM1, ABCB11, PIGS DAO 995/4885DDO 1823/4885BRD4 4083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.