Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 3/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5079778 | 1.00 | IKBKE (0.36) | IKBKETBK1KDM4EMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL1251887 | 0.99 | IKBKE (0.36) | IKBKETBK1KDM4EMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL1251890 | 0.99 | IKBKE (0.36) | IKBKETBK1KDM4EMAPTALDH1A1 | |
| SCHEMBL5079756 | 0.82 | KDM4E (0.38) | KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5079762 | 0.82 | KDM4E (0.38) | KDM4EMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1253910 | 0.81 | KDM4E (0.39) | KDM4EMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1253912 | 0.81 | KDM4E (0.39) | KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5079082 | 0.77 | SMN1; SMN2 (0.39) | KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL726656 | 0.76 | BMP1 (0.37) | — | |
| SCHEMBL726657 | 0.76 | BMP1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608377-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF FAB I AND FURTHER ANTIBIOTICS | AFFINIUM PHARM INC (CA) | 2008-10-01 | — | — | EP | claimed |