Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28577685 | 0.95 | — | — | |
| SCHEMBL11112367 | 0.86 | CA2 (0.60) | CA2CA4SLC22A16CA1FFAR3 | |
| SCHEMBL10902049 | 0.80 | CA2 (0.68) | CA2CA4SLC22A16CA1FFAR3 | |
| SCHEMBL3911447 | 0.80 | CA2 (0.60) | CA2CA4SLC22A16CA1FFAR3 | |
| SCHEMBL11112756 | 0.80 | CA2 (0.60) | CA2CA4SLC22A16CA1FFAR3 | |
| SCHEMBL14109596 | 0.80 | CA2 (0.60) | CA2CA4SLC22A16CA1FFAR3 | |
| Silver SCHEMBL6738236 | 0.80 | CA2 (0.60) | CA2CA4SLC22A16CA1FFAR3 | |
| SCHEMBL6739831 | 0.80 | CA2 (0.60) | CA2CA4SLC22A16CA1FFAR3 | |
| SCHEMBL15309768 | 0.80 | CA2 (0.48) | CA2CA4SLC22A16CA1FFAR3 | |
| Tetrabuthylammonium SCHEMBL21833984 | 0.80 | SLC22A1 (0.44) | CA2CA1CPT2CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745095-B1 | POLYMER SHEETS AND METHODS OF CONTROLLING ADHESION OF POLYMER SHEETS TO GLASS | SOLUTIA INC (US) | 2008-12-24 | — | — | EP | disclosed |