⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163586 | 0.73 | — | — | |
| SCHEMBL8003164 | 0.72 | — | — | |
| SCHEMBL5071748 | 0.71 | — | — | |
| SCHEMBL9859739 | 0.70 | MMP9 (0.31) | — | |
| SCHEMBL28316266 | 0.68 | ALDH1A1 (0.30) | — | |
| SCHEMBL28246274 | 0.68 | TSHR (0.31) | — | |
| SCHEMBL11319452 | 0.67 | — | — | |
| SCHEMBL540782 | 0.66 | — | — | |
| SCHEMBL16308973 | 0.66 | — | — | |
| SCHEMBL19074297 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778768-B1 | INTEGRALLY MOLDED BODY OF SILICONE RESIN AND SILICONE RUBBER, METHOD OF MANUFACTURE, AND CURABLE SILICONE RESIN COMPOSITION | DOW CORNING TORAY CO LTD (JP) | 2011-12-28 | — | — | EP | disclosed |
| CN-100590141-C | Integrally molded body of silicone resin and silicone rubber, method of manufacture, and curable organic silicone resin composition | DOW CORNING TORAY CO LTD | 2010-02-17 | — | — | CN | disclosed |
| US-20080255304-A1 | Integrally Molded Body of Silicone Resin and Silicone Rubber, Method of Manufacture, and Curable Silicone Resin Composition | DOW CORNING TORAY CO., LTD. (JP) | 2008-10-16 | — | — | US | disclosed |
| CN-1993408-A | Integrally molded body of silicone resin and silicone rubber, method of manufacture, and curable organic silicone resin composition | DOW CORNING TORAY CO LTD (JP) | 2007-07-04 | — | — | CN | disclosed |
| EP-1778768-A2 | INTEGRALLY MOLDED BODY OF SILICONE RESIN AND SILICONE RUBBER, METHOD OF MANUFACTURE, AND CURABLE SILICONE RESIN COMPOSITION | Dow Corning Toray Co., Ltd. (JP) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006001458-A2 | INTEGRALLY MOLDED BODY OF SILICONE RESIN AND SILICONE RUBBER, METHOD OF MANUFACTURE, AND CURABLE SILICONE RESIN COMPOSITION | DOW CORNING TORAY CO., LTD. (JP) | 2006-01-05 | — | — | WO | disclosed |