SCHEMBL5080344

SCHEMBL5080344

CC(C)=C(C(=O)O)c1ccccc1COc1cc(Cl)c(Oc2ccc(C#N)cc2)c(Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.41
MAOA P21397 1/20 0.41
PTGER4 P35408 1/20 0.39
NR4A2 P43354 2/20 0.39
PDCD1 Q15116 2/20 0.38
CD274 Q9NZQ7 2/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
FFAR1 O14842 2/20 0.37
MRGPRX4 Q96LA9 2/20 0.37
PGR P06401 2/20 0.37
TP53 P04637 1/20 0.37
HTT P42858 1/20 0.37
PTPRC P08575 1/20 0.36
PTPN1 P18031 1/20 0.36
PKM P14618 1/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
THRA P10827 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5080347 0.92 PDCD1 (0.40) MAOBMAOAPTGER4NR4A2PDCD1
SCHEMBL6151188 0.86 PTGER4 (0.39) MAOBMAOAPTGER4NR4A2NPC1
SCHEMBL5080371 0.84 MRGPRX4 (0.43) MAOBMAOAFFAR1MRGPRX4THRB
SCHEMBL6151189 0.84 PTGER4 (0.38) MAOBMAOAPTGER4NR4A2NPC1
SCHEMBL6151185 0.84 PTGER4 (0.38) MAOBMAOAPTGER4NR4A2NPC1
SCHEMBL5074556 0.84 HTT (0.41) MAOBMAOANR4A2NPC1RAB9A
SCHEMBL5080481 0.83 OPRL1 (0.42) MAOBMAOAPKMMAPK1SMN1; SMN2
SCHEMBL5080576 0.83 PGR (0.38) MAOBMAOAPTGER4NR4A2NPC1
SCHEMBL5075842 0.80 HIF1A (0.44) MAOBMAOANR4A2NPC1RAB9A
SCHEMBL5076494 0.80 TP53 (0.42) MAOBMAOANR4A2PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT MAOB 1413/4885MAOA 2407/4885PTGER4 4292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.