SCHEMBL5080347

SCHEMBL5080347

COC(C)=C(C(=O)O)c1ccccc1COc1cc(Cl)c(Oc2ccc(C#N)cc2)c(Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 6/20 0.40
CD274 Q9NZQ7 6/20 0.40
MAOB P27338 2/20 0.39
MAOA P21397 1/20 0.39
PKM P14618 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
PTGER4 P35408 1/20 0.38
NR4A2 P43354 2/20 0.38
OPRL1 P41146 2/20 0.37
PGR P06401 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
FFAR1 O14842 1/20 0.36
SCN9A Q15858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5080344 0.92 MAOB (0.41) PDCD1CD274MAOBMAOAPKM
SCHEMBL5080372 0.85 OPRL1 (0.44) MAOBMAOAOPRL1MRGPRX4FFAR1
SCHEMBL6151188 0.85 PTGER4 (0.39) MAOBMAOAPKMMAPK1SMN1; SMN2
SCHEMBL5074560 0.84 HTT (0.42) MAOBMAOASMN1; SMN2NR4A2OPRL1
SCHEMBL6151185 0.84 PTGER4 (0.38) MAOBMAOAPTGER4NR4A2PGR
SCHEMBL5080482 0.84 OPRL1 (0.45) MAOBPKMSMN1; SMN2RXFP1OPRL1
SCHEMBL6151189 0.84 PTGER4 (0.38) MAOBMAOAPTGER4NR4A2PGR
SCHEMBL5080572 0.81 HIF1A (0.56) PDCD1CD274MAOBMAOAPTGER4
SCHEMBL5080576 0.81 PGR (0.38) MAOBMAOAPTGER4NR4A2PGR
SCHEMBL5080342 0.81 HIF1A (0.37) PDCD1CD274MAOBMAOAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT PDCD1 1930/4885CD274 1960/4885MAOB 1413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.