Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 7/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL3203 | 0.94 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| SCHEMBL7049978 | 0.81 | SLC6A4 (0.58) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| SCHEMBL3204 | 0.81 | PPARG (0.41) | SLC6A9PPARGPPARAKDM4EMAOB | |
| SCHEMBL17284122 | 0.75 | SLC7A5 (0.74) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| SCHEMBL19668678 | 0.72 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| Oxalic Acid SCHEMBL8718092 | 0.72 | PPARG (0.44) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| SCHEMBL6005590 | 0.70 | SLC6A9 (0.58) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| Oxalic Acid SCHEMBL8718096 | 0.69 | PPARG (0.46) | SLC6A9PPARGPPARAKDM4E | |
| SCHEMBL14415675 | 0.69 | SLC7A5 (0.60) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| SCHEMBL5162821 | 0.69 | SLC7A5 (0.60) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133884-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | COMBINATORX, INCORPORATED (US) | 2008-11-06 | — | — | WO | disclosed |