Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16672909 | 0.86 | POLB (0.47) | POLBSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL17352103 | 0.83 | MTNR1B (0.47) | POLBSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL30909436 | 0.82 | CA1 (0.62) | POLBSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL8579858 | 0.82 | CA1 (0.62) | POLBSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL5084814 | 0.82 | TDP1 (0.45) | SMN1; SMN2ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL1130571 | 0.79 | CA1 (0.52) | POLBSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL4643953 | 0.79 | MAPT (0.57) | POLBSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL27852383 | 0.78 | MAPT (0.55) | POLBSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL27853483 | 0.77 | CA1 (0.54) | POLBSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL7971406 | 0.77 | CA1 (0.54) | POLBSMN1; SMN2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1752475-B1 | Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications | NIPPON CATALYTIC CHEM IND (JP) | 2008-11-05 | — | — | EP | disclosed |
| US-20070037962-A1 | Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-02-15 | — | — | US | disclosed |
| EP-1752475-A1 | Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-02-14 | — | — | EP | disclosed |