SCHEMBL5080586

SCHEMBL5080586

CCON=C(C(=O)O)c1ccccc1COc1cc(Cl)c(Oc2ccc(C(F)(F)F)cc2)c(Cl)c1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 4/20 0.43
MRGPRX4 Q96LA9 6/20 0.43
PPARD Q03181 5/20 0.40
OPRL1 P41146 1/20 0.40
THRB P10828 1/20 0.38
PPARA Q07869 3/20 0.38
DDR1 Q08345 1/20 0.38
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
PPARG P37231 3/20 0.37
ALOX5 P09917 1/20 0.36
PSEN1 P49768 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6149076 0.92 HIF1A (0.52) HIF1AMRGPRX4PPARDOPRL1THRB
SCHEMBL6149075 0.92 HIF1A (0.52) HIF1AMRGPRX4PPARDOPRL1THRB
SCHEMBL5076419 0.89 MAPK1 (0.41) HIF1AMRGPRX4
SCHEMBL5080576 0.85 PGR (0.38) HIF1AMRGPRX4FFAR1
SCHEMBL5079550 0.85 OPRL1 (0.40) HIF1AOPRL1
SCHEMBL5080584 0.84 HIF1A (0.63) HIF1AMRGPRX4PPARDOPRL1THRB
SCHEMBL5075954 0.83 HIF1A (0.39) HIF1AMRGPRX4DDR1FFAR1
SCHEMBL5080371 0.83 MRGPRX4 (0.43) MRGPRX4PPARDOPRL1THRBPPARA
SCHEMBL5077016 0.82 HIF1A (0.52) HIF1AMRGPRX4PPARDOPRL1THRB
SCHEMBL5077022 0.82 HIF1A (0.52) HIF1AMRGPRX4PPARDOPRL1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT HIF1A 4554/4885MRGPRX4 989/4885PPARD 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.