SCHEMBL6149076

SCHEMBL6149076

CON=C(C(=O)O)c1ccccc1COc1cc(Cl)c(Oc2ccc(C(F)(F)F)cc2)c(Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 0.52
MRGPRX4 Q96LA9 4/20 0.41
OPRL1 P41146 1/20 0.40
THRB P10828 1/20 0.39
PPARD Q03181 4/20 0.38
PPARA Q07869 2/20 0.38
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
PPARG P37231 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6149075 1.00 HIF1A (0.52) HIF1AMRGPRX4OPRL1THRBPPARD
SCHEMBL5080586 0.92 HIF1A (0.43) HIF1AMRGPRX4OPRL1THRBPPARD
SCHEMBL5080584 0.92 HIF1A (0.63) HIF1AMRGPRX4OPRL1THRBPPARD
SCHEMBL5077016 0.90 HIF1A (0.52) HIF1AMRGPRX4OPRL1THRBPPARD
SCHEMBL5077022 0.90 HIF1A (0.52) HIF1AMRGPRX4OPRL1THRBPPARD
SCHEMBL6151253 0.89 HIF1A (0.49) HIF1AMRGPRX4
SCHEMBL6151255 0.89 HIF1A (0.49) HIF1AMRGPRX4
SCHEMBL5075854 0.87 HIF1A (0.51) HIF1AMRGPRX4
SCHEMBL5075857 0.87 HIF1A (0.51) HIF1AMRGPRX4
SCHEMBL5079449 0.85 HIF1A (0.50) HIF1AMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP disclosed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO disclosed