Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.43 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.43 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11590743 | 0.81 | RAPGEF4 (0.49) | EGFRHSD17B10TNNI3TNNT2TNNC1 | |
| SCHEMBL28420297 | 0.81 | EGFR (0.54) | EGFRHSD17B10LMNAHPGDHIF1A | |
| SCHEMBL27988206 | 0.79 | IDH1 (0.44) | LMNAL3MBTL1GAAALDH1A1CASP6 | |
| SCHEMBL27562607 | 0.74 | EGFR (0.58) | EGFRHSD17B10LMNAHPGDHIF1A | |
| SCHEMBL30032694 | 0.74 | SNCA (0.50) | EGFRHSD17B10LMNAHPGDHIF1A | |
| SCHEMBL23796514 | 0.74 | SNCA (0.50) | EGFRHSD17B10LMNAHPGDHIF1A | |
| SCHEMBL30483899 | 0.74 | POLB (0.50) | EGFRHSD17B10LMNAHPGDHIF1A | |
| SCHEMBL1805528 | 0.74 | POLB (0.50) | EGFRHSD17B10LMNAHPGDHIF1A | |
| Dobesilic Acid SCHEMBL232087 | 0.73 | LMNA (0.72) | EGFRHSD17B10LMNAHPGDHIF1A | |
| SCHEMBL1535883 | 0.73 | HSD17B10 (0.52) | EGFRHSD17B10LMNAHPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335411-B2 | Method of producing a tire composition having improved silica reinforcement | BRIDGESTONE CORPORATION (JP) | 2008-02-26 | — | — | US | disclosed |
| US-20060089446-A1 | Method of producing a tire composition having improved silica reinforcement | BRIDGESTONE CORPORATION | 2006-04-27 | — | — | US | disclosed |