Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.33 |
| ▸ | PIM1 | P11309 | 4/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5083527 | 0.80 | LNPEP (0.38) | — | |
| SCHEMBL5078981 | 0.77 | NPSR1 (0.38) | HPGDNR3C2DPP4ALOX5 | |
| SCHEMBL1591434 | 0.77 | NTRK1 (0.33) | GRIN3BGRIN1GRIN2CNTRK1PIM1 | |
| SCHEMBL4601709 | 0.77 | NTRK1 (0.38) | NR3C2GRIN3BGRIN1GRIN2CNTRK1 | |
| SCHEMBL9208485 | 0.77 | RPS6KB1 (0.36) | KDM4ENR3C2GRIN3BGRIN1GRIN2C | |
| Hydrochloric Acid SCHEMBL28042958 | 0.76 | GRIN3B (0.32) | GRIN3BGRIN1GRIN2CNTRK1PIM1 | |
| SCHEMBL31046821 | 0.73 | PDE3B (0.38) | PDE3BPDE3AKDM4EUSP2HPGD | |
| SCHEMBL10647365 | 0.71 | KDM4E (0.48) | KDM4EHPGDHSD17B10POLBL3MBTL1 | |
| SCHEMBL5739044 | 0.71 | PDE3B (0.41) | PDE3BPDE3AHPGDDPP4DPP8 | |
| SCHEMBL14857133 | 0.71 | MEN1 (0.47) | KDM4ENTRK1PIM1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132505-A1 | Combination Of Cb2 Modulators And Pde4 Inhibitors For Use In Medicine | GLAXO GROUP LIMITED | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132505-A1 | Combination Of Cb2 Modulators And Pde4 Inhibitors For Use In Medicine | CNR2, CNR1, PDE4A | PDE3B 17/4885PDE3A 20/4885KDM4E 1501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.