SCHEMBL5080920

SCHEMBL5080920

COC(=O)C12CC3(C(=O)O)CC(C(=O)OC)(C1)CC(C(=O)OC)(C3)C2

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
GRM1 Q13255 2/20 0.37
NPSR1 Q6W5P4 1/20 0.35
LMNA P02545 1/20 0.35
CHRM1 P11229 1/20 0.32
FFAR3 O14843 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ALDH1A1 P00352 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20851067 1.00 MEN1 (0.37) MEN1KMT2AGRM1NPSR1LMNA
SCHEMBL5080834 1.00 MEN1 (0.37) MEN1KMT2AGRM1NPSR1LMNA
SCHEMBL9143861 1.00 MEN1 (0.37) MEN1KMT2AGRM1NPSR1LMNA
SCHEMBL5080951 1.00 MEN1 (0.37) MEN1KMT2AGRM1NPSR1LMNA
SCHEMBL5084605 0.89 NPSR1 (0.41) MEN1KMT2ANPSR1LMNACHRM1
SCHEMBL6231175 0.89 TSHR (0.44) MEN1KMT2AGRM1NPSR1LMNA
SCHEMBL9154034 0.89 NPSR1 (0.41) MEN1KMT2ANPSR1LMNACHRM1
SCHEMBL21404239 0.86 NPSR1 (0.38) MEN1KMT2AGRM1NPSR1LMNA
SCHEMBL1536077 0.86 NPSR1 (0.38) MEN1KMT2AGRM1NPSR1LMNA
SCHEMBL16875558 0.86 NPSR1 (0.38) MEN1KMT2AGRM1NPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1462471-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2008-07-30 EP disclosed
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-20070032556-A1 Aromatic polyamine derivative DAICEL CHEMICAL INSUSTRIES, LTD. (JP) 2007-02-08 US disclosed
EP-1683822-A1 PREPOLYMER, PREPOLYMER COMPOSITION, HIGH MOLECULAR WEIGHT POLYMER HAVING STRUCTURE CONTAINING HOLE AND ELECTRICALLY INSULATING FILM Daicel Chemical Industries, Ltd. (JP) 2006-07-26 EP disclosed
EP-1681284-A1 AROMATIC POLYAMINE DERIVATIVE Daicel Chemical Industries, Ltd. (JP) 2006-07-19 EP disclosed
EP-1462471-A1 Dielectric films and materials thereof Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed
US-20040175858-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032556-A1 Aromatic polyamine derivative SRM, PRMT1, KDM8 MEN1 1236/4885KMT2A 243/4885GRM1 2375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.