SCHEMBL6231175 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	1/20	0.44

▸	HSD17B10	Q99714	1/20	0.44

▸	PKM	P14618	1/20	0.43

▸	SMN1; SMN2	Q16637	2/20	0.42

▸	RAB9A	P51151	1/20	0.42

▸	MEN1	O00255	1/20	0.36

▸	KMT2A	Q03164	1/20	0.36

▸	ALDH1A1	P00352	1/20	0.36

▸	LMNA	P02545	3/20	0.35

▸	MAPT	P10636	2/20	0.35

▸	NPSR1	Q6W5P4	1/20	0.35

▸	GAA	P10253	1/20	0.34

▸	ALOX12	P18054	1/20	0.32

▸	GRM1	Q13255	2/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4037047	0.92	PKM (0.50)	TSHRHSD17B10PKMSMN1; SMN2RAB9A
SCHEMBL4037265	0.89	PKM (0.52)	TSHRHSD17B10PKMSMN1; SMN2RAB9A
SCHEMBL20851067	0.89	MEN1 (0.37)	TSHRHSD17B10MEN1KMT2AALDH1A1
SCHEMBL9143861	0.89	MEN1 (0.37)	TSHRHSD17B10MEN1KMT2AALDH1A1
SCHEMBL5080834	0.89	MEN1 (0.37)	TSHRHSD17B10MEN1KMT2AALDH1A1
SCHEMBL5080920	0.89	MEN1 (0.37)	TSHRHSD17B10MEN1KMT2AALDH1A1
SCHEMBL5080951	0.89	MEN1 (0.37)	TSHRHSD17B10MEN1KMT2AALDH1A1
SCHEMBL6231172	0.88	TSHR (0.36)	TSHRHSD17B10PKMSMN1; SMN2RAB9A
SCHEMBL20345497	0.87	TSHR (0.48)	TSHRHSD17B10PKMSMN1; SMN2RAB9A
SCHEMBL2745710	0.85	PKM (0.56)	TSHRHSD17B10PKMSMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1602975-A1	RADIATION-SENSITIVE RESIN COMPOSITION	JSR Corporation (JP)	2005-12-07	—	—	EP	disclosed