Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.80 |
| ▸ | CREB1 | P16220 | 6/20 | 0.80 |
| ▸ | PTPRS | Q13332 | 3/20 | 0.80 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.80 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.80 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.80 |
| ▸ | GABRP | O00591 | 2/20 | 0.80 |
| ▸ | GABRD | O14764 | 2/20 | 0.80 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.80 |
| ▸ | FBP1 | P09467 | 2/20 | 0.80 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.80 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.80 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.80 |
| ▸ | UGT1A1 | P22309 | 2/20 | 0.80 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.80 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.80 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.80 |
| ▸ | GRK6 | P43250 | 2/20 | 0.80 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.80 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Baicalein SCHEMBL28504707 | 0.91 | CREB1 (0.86) | ABCB1CREB1PTPRSPRSS1PRSS2 | |
| Baicalein SCHEMBL28365951 | 0.90 | ABCB1 (0.94) | ABCB1CREB1PTPRSPRSS1PRSS2 | |
| Baicalein SCHEMBL29385549 | 0.89 | ABCB1 (1.00) | ABCB1CREB1PTPRSPRSS1PRSS2 | |
| Baicalein SCHEMBL139617 | 0.89 | ABCB1 (1.00) | ABCB1CREB1PTPRSPRSS1PRSS2 | |
| Baicalein SCHEMBL5695785 | 0.89 | ABCB1 (1.00) | ABCB1CREB1PTPRSPRSS1PRSS2 | |
| Baicalein SCHEMBL29200817 | 0.89 | CREB1 (0.82) | ABCB1CREB1PTPRSPRSS1PRSS2 | |
| Baicalein SCHEMBL28372093 | 0.88 | ABCB1 (0.97) | ABCB1CREB1PTPRSPRSS1PRSS2 | |
| Baicalein SCHEMBL28826034 | 0.88 | ABCB1 (0.97) | ABCB1CREB1PTPRSPRSS1PRSS2 | |
| Baicalein SCHEMBL28630648 | 0.88 | ABCB1 (0.97) | ABCB1CREB1PTPRSPRSS1PRSS2 | |
| Baicalein SCHEMBL28198926 | 0.88 | ABCB1 (0.97) | ABCB1CREB1PTPRSPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176932-A1 | Pharmaceutical Compositions Containing Baicalein And Baicalin With Synergistic Effect In Tumor Treatment | SHANGHAI GLORIAYX BIOPHARMACEUTICALS CO., LTD. (CN) | 2008-07-24 | — | — | US | disclosed |
| EP-1849467-A1 | THE SYNERGISTICALLY PHARMACEUTICAL COMPOSITION OF BAICALEIN AND BAICALIN FOR INHIBITING TUMOR | Shanghai Gloriayx Biopharmaceuticals Co., Ltd (CN) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176932-A1 | Pharmaceutical Compositions Containing Baicalein And Baicalin With Synergistic Effect In Tumor Treatment | UGT1A1, UGT2B7, CYP11B1 | ABCB1 46/4885CREB1 3442/4885PTPRS 4458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.