SCHEMBL5081324

SCHEMBL5081324

O=C1C(F)(F)C(F)(F)C(=O)C(F)(F)C1(F)F

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
HSP90AA1 P07900 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
ALOX12 P18054 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3746961 0.82
SCHEMBL5075439 0.82
SCHEMBL2146960 0.82
SCHEMBL9936034 0.79 MEN1 (0.31)
SCHEMBL196743 0.79 MEN1 (0.31)
SCHEMBL8770624 0.79 MEN1 (0.31)
SCHEMBL5075402 0.70
SCHEMBL5078792 0.69
SCHEMBL5077499 0.61
SCHEMBL11800164 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3996200-A C,PPERFLUORINATED PARA-DIKETONE POLYMERSTHERMAL STABILITY, ELASTOMERS THE DOW CHEMICAL COMPANY (US) 1976-12-07 US claimed
US-3931325-A INTERMEDIATES FOR THERMALLY STABLE ELASTOMERS THE DOW CHEMICAL COMPANY (US) 1976-01-06 US claimed
US-20080274334-A1 Dry Etching Gas and Method of Dry Etching NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-11-06 US disclosed
CN-101015044-A Dry etching gases and method of dry etching NAT INST OF ADVANCED IND SCIEN (JP) 2007-08-08 CN disclosed
EP-1760769-A1 DRY ETCHING GASES AND METHOD OF DRY ETCHING National Institute of Advanced Industrial Science and Technology (JP) 2007-03-07 EP disclosed
US-3996200-A C,PPERFLUORINATED PARA-DIKETONE POLYMERSTHERMAL STABILITY, ELASTOMERS THE DOW CHEMICAL COMPANY (US) 1976-12-07 US disclosed
US-3996200-A C,PPERFLUORINATED PARA-DIKETONE POLYMERSTHERMAL STABILITY, ELASTOMERS THE DOW CHEMICAL COMPANY (US) 1976-12-07 US disclosed
US-3931325-A INTERMEDIATES FOR THERMALLY STABLE ELASTOMERS THE DOW CHEMICAL COMPANY (US) 1976-01-06 US disclosed
US-3931325-A INTERMEDIATES FOR THERMALLY STABLE ELASTOMERS THE DOW CHEMICAL COMPANY (US) 1976-01-06 US disclosed
US-3931325-A INTERMEDIATES FOR THERMALLY STABLE ELASTOMERS THE DOW CHEMICAL COMPANY (US) 1976-01-06 US disclosed