SCHEMBL5081346

SCHEMBL5081346

O=C(O)C[C@H](Cc1ccccc1)[C@H](CC(=O)O)Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPA3 P15088 3/20 0.64
CPA1 P15085 2/20 0.64
CPB1 P15086 1/20 0.64
CPB2 Q96IY4 1/20 0.64
CYP1A2 P05177 1/20 0.56
MIF P14174 1/20 0.53
KEAP1 Q14145 1/20 0.52
ALPI P09923 1/20 0.52
PKM P14618 1/20 0.52
PTGS1 P23219 1/20 0.52
XIAP P98170 1/20 0.52
SLC7A5 Q01650 1/20 0.52
MDM2 Q00987 1/20 0.50
AKR1B1 P15121 1/20 0.50
LTA4H P09960 2/20 0.49
SLC15A1 P46059 1/20 0.48
FOLH1 Q04609 1/20 0.48
FFAR1 O14842 1/20 0.48
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5081348 1.00 CPA3 (0.64) CPA3CPA1CPB1CPB2CYP1A2
SCHEMBL5513603 0.88 CPA1 (0.56) CPA3CPA1CPB1CPB2CYP1A2
SCHEMBL22556247 0.88 CPA1 (0.56) CPA3CPA1CPB1CPB2CYP1A2
SCHEMBL9755797 0.86 CPA1 (0.55) CPA3CPA1CPB1CPB2CYP1A2
SCHEMBL1101111 0.85 SLC1A3 (0.61) CPA3CPA1CPB1CPB2CYP1A2
SCHEMBL4367490 0.85 SLC1A3 (0.61) CPA3CPA1CPB1CPB2CYP1A2
SCHEMBL27348647 0.83 CPA1 (0.51) CPA3CPA1CPB1CPB2CYP1A2
SCHEMBL28554400 0.83 CPA1 (0.51) CPA3CPA1CPB1CPB2CYP1A2
SCHEMBL11460484 0.82 CPA3 (0.64) CPA3CPA1CPB1CPB2CYP1A2
SCHEMBL6176552 0.82 CPA3 (0.64) CPA3CPA1CPB1CPB2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1912936-A2 STEREOSELECTIVE SYNTHESIS OF 3,4-DISUBSTITUTED CYCLOPENTANONES AND RELATED COMPOUNDS Pharmacia & Upjohn Company LLC (US) 2008-04-23 EP claimed
WO-2007010387-A2 STEREOSELECTIVE SYNTHESIS OF 3,4-DISUBSTITUTED CYCLOPENTANONES AND RELATED COMPOUNDS PHARMACIA & UPJOHN COMPANY LLC (US) 2007-01-25 WO claimed
EP-1912936-A2 STEREOSELECTIVE SYNTHESIS OF 3,4-DISUBSTITUTED CYCLOPENTANONES AND RELATED COMPOUNDS Pharmacia & Upjohn Company LLC (US) 2008-04-23 EP disclosed
WO-2007010387-A2 STEREOSELECTIVE SYNTHESIS OF 3,4-DISUBSTITUTED CYCLOPENTANONES AND RELATED COMPOUNDS PHARMACIA & UPJOHN COMPANY LLC (US) 2007-01-25 WO disclosed