Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 2/20 | 0.55 |
| ▸ | CPB1 | P15086 | 1/20 | 0.55 |
| ▸ | CPA3 | P15088 | 1/20 | 0.55 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5513603 | 0.87 | CPA1 (0.56) | CPA1CPB1CPA3CPB2LTA4H | |
| SCHEMBL22556247 | 0.87 | CPA1 (0.56) | CPA1CPB1CPA3CPB2LTA4H | |
| SCHEMBL5081348 | 0.86 | CPA3 (0.64) | CPA1CPB1CPA3CPB2LTA4H | |
| SCHEMBL5081346 | 0.86 | CPA3 (0.64) | CPA1CPB1CPA3CPB2LTA4H | |
| SCHEMBL28554400 | 0.82 | CPA1 (0.51) | CPA1CPB1CPA3CPB2LTA4H | |
| SCHEMBL16488807 | 0.79 | CPA1 (0.60) | CPA1CPB1CPA3CPB2LTA4H | |
| SCHEMBL4437952 | 0.79 | TRPA1 (0.59) | NPC1RAB9ACYP1A2TRPA1 | |
| SCHEMBL15219955 | 0.79 | TRPA1 (0.60) | NPC1RAB9ATRPA1 | |
| SCHEMBL14542152 | 0.79 | CPA1 (0.60) | CPA1CPB1CPA3CPB2LTA4H | |
| SCHEMBL750878 | 0.79 | CPA1 (0.60) | CPA1CPB1CPA3CPB2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005763-A1 | DIPEPTIDE-ANALOG-BASED METALLOENDOPEPTIDASE INHIBITORS AND METHODS OF USING SAME | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |