SCHEMBL5081832

SCHEMBL5081832

CC(=O)Nc1cc(NC(C)=O)c(Nc2ccccc2)cc1Nc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.63
POLB P06746 2/20 0.63
HSD17B10 Q99714 2/20 0.61
NAPRT Q6XQN6 1/20 0.61
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
TAAR1 Q96RJ0 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.51
GAA P10253 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HPGD P15428 1/20 0.50
SIRT2 Q8IXJ6 1/20 0.50
AKR1C3 P42330 1/20 0.50
AKR1C2 P52895 1/20 0.50
GFER P55789 3/20 0.49
CYP2C19 P33261 2/20 0.49
HDAC1 Q13547 2/20 0.49
KDM4E B2RXH2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5078720 1.00 MAPT (0.63) MAPTPOLBHSD17B10NAPRTKMT2A
SCHEMBL20631546 0.86 MAPT (0.66) MAPTPOLBHSD17B10NAPRTKMT2A
SCHEMBL339128 0.83 ALDH1A1 (0.55) MAPTPOLBHSD17B10NAPRTKMT2A
SCHEMBL5085272 0.81 HPGD (0.53) MAPTPOLBHSD17B10KMT2AMEN1
SCHEMBL5085409 0.81 HPGD (0.53) MAPTPOLBHSD17B10KMT2AMEN1
SCHEMBL21697479 0.81 AKR1C3 (0.65) MAPTHSD17B10KMT2AMEN1SMN1; SMN2
SCHEMBL14339397 0.80 POLB (0.62) MAPTPOLBHSD17B10NAPRTKMT2A
SCHEMBL5080930 0.78 HSD17B10 (0.65) MAPTHSD17B10KMT2AMEN1SMN1; SMN2
SCHEMBL5080845 0.78 POLB (0.54) MAPTPOLBHSD17B10NAPRTKMT2A
SCHEMBL9480198 0.78 MAPT (1.00) MAPTPOLBHSD17B10NAPRTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1462471-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2008-07-30 EP disclosed
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 US disclosed
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 US disclosed
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
EP-1462471-A1 Dielectric films and materials thereof Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed
US-20040175858-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-09 US disclosed