SCHEMBL5081987

SCHEMBL5081987

N#Cc1ccccc1NC(=O)c1cc(Cl)ns1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.48
ALDH1A1 P00352 5/20 0.48
GAA P10253 5/20 0.48
ALOX15 P16050 2/20 0.48
HSD17B10 Q99714 2/20 0.48
GLA P06280 1/20 0.48
HPGD P15428 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
THRB P10828 2/20 0.47
RAB9A P51151 5/20 0.46
NPC1 O15118 4/20 0.46
KMT2A Q03164 4/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
TSHR P16473 3/20 0.46
HTT P42858 2/20 0.46
MEN1 O00255 2/20 0.46
TP53 P04637 1/20 0.46
EPHB3 P54753 1/20 0.45
LMNA P02545 2/20 0.44
MAPT P10636 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28188512 0.77 KDM4E (0.49) KDM4EALDH1A1GAAALOX15HSD17B10
SCHEMBL4149781 0.76 KDM4E (0.48) KDM4EALDH1A1GAAALOX15HSD17B10
SCHEMBL29395460 0.76 ALDH1A1 (0.48) KDM4EALDH1A1GAAALOX15HSD17B10
SCHEMBL22380 0.76 ALDH1A1 (0.48) KDM4EALDH1A1GAAALOX15HSD17B10
SCHEMBL27463333 0.76 HTT (0.49) KDM4EALDH1A1GAAHPGDRAB9A
SCHEMBL16369377 0.74 GAA (0.48) KDM4EALDH1A1GAAALOX15HSD17B10
SCHEMBL20104490 0.74 ALDH1A1 (0.48) KDM4EALDH1A1GAAALOX15HSD17B10
SCHEMBL24093709 0.74 KDM4E (0.49) KDM4EALDH1A1GAAALOX15HSD17B10
SCHEMBL27685958 0.73 KDM4E (0.46) KDM4EALDH1A1GAAALOX15HSD17B10
SCHEMBL28844863 0.73 KMT2A (0.76) KDM4EALDH1A1GAAHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101528040-B Fungicidal and insecticidal compositions BAYER CROPSCIENCE AG 2013-01-02 CN claimed
CN-101917856-A Combinations comprising a fungicidal strain and an active compound BASF SE 2010-12-15 CN claimed
CN-101909442-A Fungicidal mixtures comprising a substituted 3-hydroxymethylpyridine and another fungicidal compound BASF SE 2010-12-08 CN claimed
CN-101909451-A Fungicidal mixtures II BASF SE 2010-12-08 CN claimed
CN-101909452-A Fungicidal mixtures III BASF SE 2010-12-08 CN claimed
CN-101822260-A Fungicidal mixture BASF SE 2010-09-08 CN claimed
CN-101808521-A ternary fungicidal compositions comprising boscalid and chlorothalonil BASF SE 2010-08-18 CN claimed
CN-101677566-A fungicidal mixtures BASF SE 2010-03-24 CN claimed
CN-101631465-A Fungicidal mixtures comprising substituted 1-methylpyrazol-4-ylcarboxanilides BASF SE 2010-01-20 CN claimed
CN-101605461-A Pesticidal mixtures BASF SE (DE) 2009-12-16 CN claimed
CN-101217873-A Fungicidal mixtures made from 1-methylpyrazol-4-ylcarboxanilides BASF AG (DE) 2008-07-09 CN claimed
CN-101212901-A Fungicidal mixtures based on 2,5-disubstituted pyrazol carboxylic acid biphenylamides BASF AG (DE) 2008-07-02 CN claimed
CN-101212902-A Fungicidal mixtures based on 3, 5-disubstituted pyrazole carboxylic acid biphenylamides BASF AG (DE) 2008-07-02 CN claimed
CN-101212900-A Fungicide mixtures based on 2,4-disubstituted pyrazole carboxylic acid biphenylamides BASF AG (DE) 2008-07-02 CN claimed
CN-101184391-A Substance combinations with synergistic fungicidal activity BAYER CROPSCIENCE AG (DE) 2008-05-21 CN claimed
CN-101087530-A Fungicidal mixtures BASF AG (DE) 2007-12-12 CN claimed
CN-101087529-A Fungicidal mixtures BASF AG (DE) 2007-12-12 CN claimed
CN-101080169-A Fungicide composition BASF AG (DE) 2007-11-28 CN claimed
CN-1325483-C Method for producing 3,4-dichloro-n-(2-cyano-phenyl)-5-isothiazole carboxamide BAYER CROPSCIENCE AG (DE) 2007-07-11 CN claimed
CN-1678595-A Method for producing 3,4-dichloro-n-(2-cyano-phenyl)-5-isothiazole carboxamide BAYER CROPSCIENCE AG (DE) 2005-10-05 CN claimed