Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16070047 | 0.77 | RAB9A (0.43) | HTTPOLBRAB9ANPC1MAPT | |
| SCHEMBL19382699 | 0.71 | HTT (0.60) | HTTUSP2POLBRAB9ANPC1 | |
| SCHEMBL9283635 | 0.71 | NPC1 (0.63) | POLBRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL11925387 | 0.71 | PTPN1 (0.59) | HTTPOLBRAB9ANPC1MAPT | |
| SCHEMBL20273850 | 0.71 | POLB (0.53) | POLBRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL9655858 | 0.71 | ALDH1A1 (0.51) | HTTPOLBRAB9ANPC1MAPT | |
| SCHEMBL22725202 | 0.71 | POLB (0.53) | HTTPOLBRAB9ANPC1MAPT | |
| SCHEMBL3264297 | 0.70 | RPS6KA3 (0.65) | HTTPOLBRAB9ANPC1MAPT | |
| SCHEMBL4152879 | 0.69 | PTPRC (0.61) | HTTPOLBRAB9ANPC1MAPT | |
| SCHEMBL23413100 | 0.69 | POLB (0.59) | HTTUSP2POLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1122028-C | Isothiazole carboxylic acid amides and the application thereof in order to proteot plants | BAYER AG (DE) | 2003-09-24 | — | — | CN | disclosed |
| CN-1278803-A | Isothiazole carboxylic acid amides and the application thereof in order to proteot plants | BAYER AG (DE) | 2001-01-03 | — | — | CN | disclosed |