Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.52 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | CLIC1 | O00299 | 1/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10316744 | 0.97 | PTGS2 (0.54) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL3881380 | 0.95 | PTGS2 (0.56) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL3871688 | 0.92 | PTGS2 (0.60) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL3869439 | 0.92 | PTGS2 (0.46) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL3873443 | 0.91 | PTGS2 (0.49) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL3871928 | 0.87 | PTGS2 (0.65) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL3873191 | 0.86 | PTGS2 (0.40) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL3872166 | 0.85 | PTGS2 (0.57) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL3881581 | 0.83 | PTGS2 (0.47) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL3871234 | 0.81 | PTGS2 (0.62) | PTGS2ABCB11PTGS1PPARGNR1I3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156645-A2 | PHARMACEUTICAL COMPOSITIONS AND USES | NOVARTIS AG (CH) | 2008-12-24 | — | — | WO | disclosed |