SCHEMBL5082291

SCHEMBL5082291

O=S(=O)(O)c1cncc(S(=O)(=O)O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.54
APLNR P35414 1/20 0.46
TSHR P16473 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KDM4E B2RXH2 2/20 0.41
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41
LMNA P02545 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
ING2 Q9H160 1/20 0.39
ALDH1A1 P00352 5/20 0.39
NT5E P21589 2/20 0.39
HSD17B10 Q99714 4/20 0.38
PTGS1 P23219 2/20 0.33
PTGS2 P35354 2/20 0.33
HPGD P15428 1/20 0.33
PIK3C3 Q8NEB9 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31344514 0.84 HCAR2 (0.45) NAPRTAPLNRKDM4EPTGS1PTGS2
SCHEMBL5149378 0.84 HCAR2 (0.45) NAPRTAPLNRTSHRSMN1; SMN2KDM4E
SCHEMBL11638312 0.84 ALDH1A1 (0.50) NAPRTAPLNRTSHRSMN1; SMN2KDM4E
SCHEMBL1347132 0.84 S100A9 (0.45) NAPRTAPLNRSMN1; SMN2KDM4EPTGS1
SCHEMBL28040445 0.84 NAPRT (0.45) NAPRTAPLNRTSHRSMN1; SMN2KDM4E
Hydrochloric Acid SCHEMBL27566402 0.82 HCAR2 (0.44) NAPRTAPLNRTSHRSMN1; SMN2KDM4E
Hydrochloric Acid SCHEMBL27899332 0.82 S100A9 (0.44) NAPRTAPLNRSMN1; SMN2KDM4EPTGS1
Hydrochloric Acid SCHEMBL28159283 0.82 HCAR2 (0.44) NAPRTAPLNRKDM4EPTGS1PTGS2
SCHEMBL11027647 0.80 LCK (0.61) NAPRTAPLNRKDM4ELCKFYN
SCHEMBL3468052 0.79 NAMPT (0.43) NAPRTAPLNRCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108610569-A A kind of computer antistatic agent and preparation method thereof 合肥酷睿网络科技有限公司 2018-10-02 CN claimed
CN-108449995-A representative diagnosis 文塔纳医疗系统公司 2018-08-24 CN disclosed
US-9269987-B2 Anions and derived salts with high dissociation in non-protogenic solvents JÓNSSON ERLENDUR (SE) 2016-02-23 US disclosed
US-20140272601-A1 Anions and Derived Salts with High Dissociation in Non-Protogenic Solvents JÓNSSON ERLENDUR (SE) 2014-09-18 US disclosed
WO-2013072470-A1 ANIONS AND DERIVED SALTS WITH HIGH DISSOCIATION IN NON-PROTOGENIC SOLVENTS JONSSON ERLENDUR (SE) 2013-05-23 WO disclosed
EP-1497374-B1 FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF GEN ELECTRIC (US) 2008-08-13 EP disclosed
US-7244778-B2 Filler reinforced polyether imide resin composition and molded article thereof GENERAL ELECTRIC COMPANY (US) 2007-07-17 US disclosed
US-20050131105-A1 Filler reinforced polyether imide resin composition and molded article thereof SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2005-06-16 US disclosed
EP-1497374-A1 FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF GENERAL ELECTRIC COMPANY (US) 2005-01-19 EP disclosed
WO-2003087226-A1 FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF GENERAL ELECTRIC COMPAMY (US) 2003-10-23 WO disclosed
EP-0603557-B1 Catalyst compositions and catalytic processes PHILLIPS PETROLEUM CO (US) 1997-07-30 EP disclosed
US-5461126-A Process of polymerizing olefins using organonickel catalyst compositions PHILLIPS PETROLEUM COMPANY (US) 1995-10-24 US disclosed
US-5332708-A Ethylene polymerization catalyst, organonickel compound and a heterocyclic nitrogen compound PHILLIPS PETROLEUM COMPANY (US) 1994-07-26 US disclosed
EP-0603557-A1 Catalyst compositions and catalytic processes PHILLIPS PETROLEUM COMPANY (US) 1994-06-29 EP disclosed
EP-0012117-B1 PROCESS FOR THE PREPARATION OF 2,3,5-TRICHLOROPYRIDINE; 2,4,4-TRICHLORO-4-FORMYL-BUTYRONITRILE AND PROCESS FOR ITS PREPARATION CIBA-GEIGY AG (CH) 1982-02-10 EP disclosed
US-4245098-A BY REACTING TRICHLOROACETALDEHYDE WITH ACRYLONITRILE CIBA-GEIGY CORPORATION (US) 1981-01-13 US disclosed
EP-0012117-A1 Process for the preparation of 2,3,5-trichloropyridine; 2,4,4-trichloro-4-formyl-butyronitrile and process for its preparation CIBA-GEIGY AG (CH) 1980-06-11 EP disclosed
US-4039509-A METAL SALTS OF HETEROCYCLIC SULFONIC ACIDS GENERAL ELECTRIC COMPANY (US) 1977-08-02 US disclosed