SCHEMBL5082333

SCHEMBL5082333

Cc1ccc([Si](C)(C)OCC(CO[Si](C)(C)c2ccc(C)cc2)(Cc2ccccc2)Cc2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.36
SLC6A2 P23975 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
HTT P42858 1/20 0.34
CYP2C19 P33261 1/20 0.34
POLB P06746 4/20 0.33
LMNA P02545 3/20 0.33
CYP2D6 P10635 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
ATM Q13315 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
RAB9A P51151 3/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
NPC1 O15118 2/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5078400 0.94 KIF11 (0.33) KIF11SLC6A2TAAR1HTTCYP2C19
SCHEMBL5080751 0.92 KIF11 (0.32) KIF11ALDH1A1
SCHEMBL5080896 0.90 SLC6A2 (0.38) SLC6A2TAAR1CYP2C19LMNACYP2D6
SCHEMBL5077368 0.89 KIF11 (0.31) KIF11
SCHEMBL5077245 0.84 SLC6A2 (0.34) SLC6A2TAAR1CYP2C19LMNACYP2D6
SCHEMBL5081653 0.82 SLC6A2 (0.33) SLC6A2TAAR1LMNACYP2D6ALDH1A1
SCHEMBL5080977 0.80 SLC6A2 (0.31) SLC6A2TAAR1
SCHEMBL5082338 0.78 SLC6A2 (0.34) SLC6A2TAAR1CYP2C19LMNACYP2D6
SCHEMBL5081776 0.78 SLC6A2 (0.42) SLC6A2TAAR1CYP2C19LMNACYP2D6
SCHEMBL5078403 0.75 SLC6A2 (0.32) SLC6A2TAAR1LMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed