SCHEMBL5081776

SCHEMBL5081776

C[Si](C)(C)OCC(CO[Si](C)(C)C)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
LMNA P02545 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TRPA1 O75762 1/20 0.35
TP53 P04637 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
TSHR P16473 1/20 0.33
FDPS P14324 1/20 0.33
MMP8 P22894 2/20 0.33
KCNA5 P22460 1/20 0.33
CALM1 P0DP23 1/20 0.32
ALDH1A1 P00352 1/20 0.32
RECQL P46063 1/20 0.32
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5077173 0.93 SLC6A2 (0.37) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5075153 0.90 SLC6A2 (0.35) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5077632 0.87 SLC6A2 (0.33) SLC6A2TAAR1LMNACYP2D6TP53
SCHEMBL5081767 0.83 TAAR1 (0.38) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5080896 0.83 SLC6A2 (0.38) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5085326 0.83 SLC6A2 (0.38) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5080967 0.83 SLC6A2 (0.42) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5080881 0.81 SLC6A2 (0.39) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5081735 0.80 TAAR1 (0.36) SLC6A2TAAR1LMNACYP2D6SMN1; SMN2
SCHEMBL5081803 0.80 SLC6A2 (0.36) SLC6A2TAAR1LMNACYP2D6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed