Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 5/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4015124 | 1.00 | MEN1 (0.61) | MEN1KMT2ARAB9AMMP2MMP9 | |
| SCHEMBL4074349 | 0.87 | KMT2A (0.57) | MEN1KMT2ARAB9AMMP2MMP9 | |
| SCHEMBL13845797 | 0.86 | POLB (0.52) | MEN1KMT2ARAB9AMMP2MMP9 | |
| SCHEMBL13845795 | 0.80 | MEN1 (0.55) | MEN1KMT2ARAB9AMMP2MMP9 | |
| SCHEMBL13845793 | 0.79 | POLB (0.55) | MEN1KMT2ARAB9AMMP2MMP9 | |
| SCHEMBL7122131 | 0.77 | MEN1 (0.54) | MEN1KMT2ARAB9AMMP2MMP9 | |
| SCHEMBL13849822 | 0.76 | POLB (0.48) | MEN1KMT2ARAB9AMMP2MMP9 | |
| SCHEMBL13845789 | 0.76 | MEN1 (0.55) | MEN1KMT2ARAB9AMMP2MMP9 | |
| SCHEMBL7069632 | 0.76 | ALDH1A1 (0.65) | MEN1KMT2ARAB9AMMP2MMP9 | |
| SCHEMBL25243550 | 0.75 | MEN1 (0.71) | MEN1KMT2ARAB9AMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008132128-A2 | SYNTHESIS OF A PHARMACEUTICALLY ACTIVE COMPOUND | Solvay (Société Anonyme) (BE) | 2008-11-06 | — | — | WO | claimed |
| WO-2008132128-A2 | SYNTHESIS OF A PHARMACEUTICALLY ACTIVE COMPOUND | Solvay (Société Anonyme) (BE) | 2008-11-06 | — | — | WO | disclosed |